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Aliases SLC6A14, BMIQ11, solute carrier family 6 member 14
External IDs MGI: 1890216 HomoloGene: 38290 GeneCards: SLC6A14
RNA expression pattern
PBB GE SLC6A14 219795 at fs.png
More reference expression data
Species Human Mouse
RefSeq (mRNA)



RefSeq (protein)



Location (UCSC) Chr X: 116.44 – 116.46 Mb Chr X: 21.71 – 21.74 Mb
PubMed search [1] [2]
View/Edit Human View/Edit Mouse

Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) (SLC6A14) is a protein that in humans is encoded by the SLC6A14 gene.[3][4]


SLC6A14 is a member of the Na+- and Cl-dependent neurotransmitter transporter family and transports both neutral and cationic amino acids in an Na+- and Cl-dependent manner.[supplied by OMIM][4]


  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Sloan JL, Mager S (Sep 1999). "Cloning and functional expression of a human Na(+) and Cl(−)-dependent neutral and cationic amino acid transporter B(0+)". J Biol Chem. 274 (34): 23740–5. PMID 10446133. doi:10.1074/jbc.274.34.23740. 
  4. ^ a b "Entrez Gene: SLC6A14 solute carrier family 6 (amino acid transporter), member 14". 

Further reading[edit]

  • Ohman M, Oksanen L, Kaprio J, Koskenvuo M, Mustajoki P, Rissanen A, Salmi J, Kontula K, Peltonen L (2000). "Genome-wide scan of obesity in Finnish sibpairs reveals linkage to chromosome Xq24". J. Clin. Endocrinol. Metab. 85 (9): 3183–90. PMID 10999806. doi:10.1210/jc.85.9.3183. 
  • Sloan JL, Grubb BR, Mager S (2003). "Expression of the amino acid transporter ATB 0+ in lung: possible role in luminal protein removal". Am. J. Physiol. Lung Cell Mol. Physiol. 284 (1): L39–49. PMID 12388375. doi:10.1152/ajplung.00164.2002. 
  • Suviolahti E, Oksanen LJ, Ohman M, Cantor RM, Ridderstrale M, Tuomi T, Kaprio J, Rissanen A, Mustajoki P, Jousilahti P, Vartiainen E, Silander K, Kilpikari R, Salomaa V, Groop L, Kontula K, Peltonen L, Pajukanta P (2004). "The SLC6A14 gene shows evidence of association with obesity". J. Clin. Invest. 112 (11): 1762–72. PMC 281637Freely accessible. PMID 14660752. doi:10.1172/JCI17491. 
  • Durand E, Boutin P, Meyre D, Charles MA, Clement K, Dina C, Froguel P (2004). "Polymorphisms in the amino acid transporter solute carrier family 6 (neurotransmitter transporter) member 14 gene contribute to polygenic obesity in French Caucasians". Diabetes. 53 (9): 2483–6. PMID 15331564. doi:10.2337/diabetes.53.9.2483. 
  • Gupta N, Miyauchi S, Martindale RG, Herdman AV, Podolsky R, Miyake K, Mager S, Prasad PD, Ganapathy ME, Ganapathy V (2005). "Upregulation of the amino acid transporter ATB0,+ (SLC6A14) in colorectal cancer and metastasis in humans". Biochim. Biophys. Acta. 1741 (1–2): 215–23. PMID 15905073. doi:10.1016/j.bbadis.2005.04.002.