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SLC8B1

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SLC8B1
Identifiers
AliasesSLC8B1, NCKX6, NCLX, SLC24A6, solute carrier family 8 member B1
External IDsOMIM: 609841; MGI: 2180781; HomoloGene: 41602; GeneCards: SLC8B1; OMA:SLC8B1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_024959
NM_001330466
NM_001358345

NM_001177594
NM_001177595
NM_133221

RefSeq (protein)

NP_001317395
NP_079235
NP_001345274

NP_001171065
NP_001171066
NP_573484

Location (UCSC)Chr 12: 113.3 – 113.36 MbChr 5: 120.65 – 120.67 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 is a protein that in humans is encoded by the SLC8B1 gene.[5]

Function

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SLC24A6 belongs to a family of Potassium-dependent sodium-calcium exchangers that maintain cellular calcium homeostasis through the electrogenic countertransport of 4 sodium ions for 1 calcium ion and 1 potassium ion.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000089060Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032754Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Solute carrier family 8 (sodium/lithium/calcium exchanger), member B1".
  6. ^ Cai X, Lytton J (February 2004). "Molecular cloning of a sixth member of the K+-dependent Na+/Ca2+ exchanger gene family, NCKX6". The Journal of Biological Chemistry. 279 (7): 5867–76. doi:10.1074/jbc.M310908200. PMID 14625281.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.