SMARCD1

SMARCD1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1UHR
Identifiers
Aliases	SMARCD1, BAF60A, CRACD1, Rsc6p, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1, CSS11
External IDs	OMIM: 601735; MGI: 1933623; HomoloGene: 20670; GeneCards: SMARCD1; OMA:SMARCD1 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	50,100,707 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	99,611,872 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; ventricular zone; ; right lobe of thyroid gland; ; left lobe of thyroid gland; ; right ovary; ; cardia; ; right hemisphere of cerebellum; ; body of uterus; ; left ovary; ; granulocyte;
	Top expressed in
	superior frontal gyrus; ; ventricular zone; ; epiblast; ; primary visual cortex; ; tail of embryo; ; neural tube; ; dentate gyrus of hippocampal formation granule cell; ; genital tubercle; ; olfactory tubercle; ; entorhinal cortex;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	molecular adaptor activity; transcription coactivator activity; chromatin binding; protein binding; signaling receptor binding;
Cellular component	npBAF complex; nBAF complex; nucleus; nucleoplasm; intracellular membrane-bounded organelle; SWI/SNF complex;
Biological process	regulation of transcription by RNA polymerase II; chromatin remodeling; nucleosome disassembly; cellular response to fatty acid; nervous system development; chromatin organization;
	Sources:Amigo / QuickGO
Orthologs
	6602
	83797
	ENSG00000066117
	ENSMUSG00000023018
	Q96GM5
	Q61466
	NM_003076; NM_139071
	NM_031842
	NP_003067; NP_620710
	NP_114030
	Wikidata
View/Edit Human	View/Edit Mouse

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 is a protein that in humans is encoded by the SMARCD1 gene.^[5]^[6]^[7]^[8]

Template:PBB Summary

Interactions

SMARCD1 has been shown to interact with Glucocorticoid receptor.^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000066117 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000023018 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Wang W, Xue Y, Zhou S, Kuo A, Cairns BR, Crabtree GR (Nov 1996). "Diversity and specialization of mammalian SWI/SNF complexes". Genes Dev. 10 (17): 2117–30. doi:10.1101/gad.10.17.2117. PMID 8804307.
^ Ring HZ, Vameghi-Meyers V, Wang W, Crabtree GR, Francke U (Sep 1998). "Five SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin (SMARC) genes are dispersed in the human genome". Genomics. 51 (1): 140–3. doi:10.1006/geno.1998.5343. PMID 9693044.
^ ^a ^b Hsiao PW, Fryer CJ, Trotter KW, Wang W, Archer TK (Aug 2003). "BAF60a mediates critical interactions between nuclear receptors and the BRG1 chromatin-remodeling complex for transactivation". Mol Cell Biol. 23 (17): 6210–20. doi:10.1128/MCB.23.17.6210-6220.2003. PMC 180928. PMID 12917342.
^ "Entrez Gene: SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1".

Interactions

References

Further reading