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SPRED3

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SPRED3
Identifiers
AliasesSPRED3, Eve-3, spred-3, sprouty related EVH1 domain containing 3
External IDsOMIM: 609293; MGI: 2142186; HomoloGene: 28061; GeneCards: SPRED3; OMA:SPRED3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001039616
NM_001042522
NM_001394336
NM_001394337
NM_001394338

NM_182927

RefSeq (protein)

NP_001035987

NP_891557

Location (UCSC)Chr 19: 38.39 – 38.4 MbChr 7: 28.86 – 28.87 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Sprouty-related, EVH1 domain-containing protein 3 also known as Spread-3 is a protein that in humans is encoded by the SPRED3 gene.[5]

Spread-3 is a member of the Sprouty (see SPRY1/SPRED) family of proteins that regulate growth factor-induced activation of the MAP kinase cascade.[5][6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000188766Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000037239Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: sprouty-related".
  6. ^ Nonami A, Kato R, Taniguchi K, Yoshiga D, Taketomi T, Fukuyama S, Harada M, Sasaki A, Yoshimura A (December 2004). "Spred-1 negatively regulates interleukin-3-mediated ERK/mitogen-activated protein (MAP) kinase activation in hematopoietic cells". The Journal of Biological Chemistry. 279 (50): 52543–51. doi:10.1074/jbc.M405189200. PMID 15465815.

Further reading

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