SV2A

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SV2A
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases SV2A, SV2, synaptic vesicle glycoprotein 2A
External IDs MGI: 1927139 HomoloGene: 32237 GeneCards: SV2A
RNA expression pattern
PBB GE SV2A 203069 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_014849
NM_001278719

NM_022030

RefSeq (protein)

NP_001265648
NP_001315603
NP_001315604
NP_055664

NP_071313.1
NP_071313

Location (UCSC) Chr 1: 149.9 – 149.92 Mb Chr 3: 96.18 – 96.2 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Synaptic vesicle glycoprotein 2A is a ubiquitous synaptic vesicle protein that in humans is encoded by the SV2A gene.[3][4][5] The protein is targeted by the anti-epileptic drugs (anticonvulsants) levetiracetam and brivaracetam.[6]

See also[edit]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Bajjalieh SM, Peterson K, Linial M, Scheller RH (Mar 1993). "Brain contains two forms of synaptic vesicle protein 2". Proceedings of the National Academy of Sciences of the United States of America. 90 (6): 2150–4. doi:10.1073/pnas.90.6.2150. PMC 46043Freely accessible. PMID 7681585. 
  4. ^ Crowder KM, Gunther JM, Jones TA, Hale BD, Zhang HZ, Peterson MR, Scheller RH, Chavkin C, Bajjalieh SM (Dec 1999). "Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A)". Proceedings of the National Academy of Sciences of the United States of America. 96 (26): 15268–73. doi:10.1073/pnas.96.26.15268. PMC 24809Freely accessible. PMID 10611374. 
  5. ^ "Entrez Gene: SV2A synaptic vesicle glycoprotein 2A". 
  6. ^ Ulloa CM, Towfigh A, Safdieh J (2009). "Review of levetiracetam, with a focus on the extended release formulation, as adjuvant therapy in controlling partial-onset seizures". Neuropsychiatric Disease and Treatment. 5: 467–76. doi:10.2147/ndt.s4844. PMC 2747386Freely accessible. PMID 19777068. 

Further reading[edit]