Salidroside

Salidroside
Names
	IUPAC name 2-(4-Hydroxyphenyl)ethyl β-D-glucopyranoside
	Other names Salidroside; Rhodioloside; (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[2-(4-hydroxyphenyl)ethoxy]oxane-3,4,5-triol; Tyrosol glucoside
Identifiers
CAS Number	10338-51-9 ;
3D model (JSmol)	Interactive image;
ChEMBL	ChEMBL465208 ;
ChemSpider	140088 ;
ECHA InfoCard	100.224.258
PubChem CID	159278;
UNII	M983H6N1S9 ;
CompTox Dashboard (EPA)	DTXSID4049034 ;
	InChI InChI=1S/C14H20O7/c15-7-10-11(17)12(18)13(19)14(21-10)20-6-5-8-1-3-9(16)4-2-8/h1-4,10-19H,5-7H2/t10-,11-,12+,13-,14-/m1/s1 Key: ILRCGYURZSFMEG-RKQHYHRCSA-N ; InChI=1/C14H20O7/c15-7-10-11(17)12(18)13(19)14(21-10)20-6-5-8-1-3-9(16)4-2-8/h1-4,10-19H,5-7H2/t10-,11-,12+,13-,14-/m1/s1 Key: ILRCGYURZSFMEG-RKQHYHRCBF;
	SMILES C1=CC(=CC=C1CCO[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)O;
Properties
Chemical formula	C14H20O7
Molar mass	300.307 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Salidroside (rhodioloside) is a glucoside of tyrosol found in the plant Rhodiola rosea.^[1] It has been studied, along with rosavin, as one of the potential compounds responsible for the putative antidepressant and anxiolytic actions of this plant.^[2]^[3] Salidroside may be more active than rosavin,^[4] even though many commercially marketed Rhodiola rosea extracts are standardized for rosavin content rather than salidroside.

References

^ Mao, Y; Li, Y; Yao, N (2007). "Simultaneous determination of salidroside and tyrosol in extracts of Rhodiola L. By microwave assisted extraction and high-performance liquid chromatography". Journal of Pharmaceutical and Biomedical Analysis. 45 (3): 510–5. doi:10.1016/j.jpba.2007.05.031. PMID 17628386.
^ Perfumi, Marina; Mattioli, Laura (2007). "Adaptogenic and central nervous system effects of single doses of 3% rosavin and 1% salidroside Rhodiola rosea L. Extract in mice". Phytotherapy Research. 21 (1): 37–43. doi:10.1002/ptr.2013. PMID 17072830.
^ Mattioli, L.; Funari, C.; Perfumi, M. (2008). "Effects of Rhodiola rosea L. Extract on behavioural and physiological alterations induced by chronic mild stress in female rats". Journal of Psychopharmacology. 23 (2): 130–142. doi:10.1177/0269881108089872. PMID 18515456.
^ Panossian, A.; Nikoyan, N.; Ohanyan, N.; Hovhannisyan, A.; Abrahamyan, H.; Gabrielyan, E.; Wikman, G. (2008). "Comparative study of Rhodiola preparations on behavioral despair of rats". Phytomedicine. 15 (1–2): 84–91. doi:10.1016/j.phymed.2007.10.003. PMID 18054474.

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[mao-1] Mao, Y; Li, Y; Yao, N (2007). "Simultaneous determination of salidroside and tyrosol in extracts of Rhodiola L. By microwave assisted extraction and high-performance liquid chromatography". Journal of Pharmaceutical and Biomedical Analysis. 45 (3): 510–5. doi:10.1016/j.jpba.2007.05.031. PMID 17628386.

[2] Perfumi, Marina; Mattioli, Laura (2007). "Adaptogenic and central nervous system effects of single doses of 3% rosavin and 1% salidroside Rhodiola rosea L. Extract in mice". Phytotherapy Research. 21 (1): 37–43. doi:10.1002/ptr.2013. PMID 17072830.

[3] Mattioli, L.; Funari, C.; Perfumi, M. (2008). "Effects of Rhodiola rosea L. Extract on behavioural and physiological alterations induced by chronic mild stress in female rats". Journal of Psychopharmacology. 23 (2): 130–142. doi:10.1177/0269881108089872. PMID 18515456.

[4] Panossian, A.; Nikoyan, N.; Ohanyan, N.; Hovhannisyan, A.; Abrahamyan, H.; Gabrielyan, E.; Wikman, G. (2008). "Comparative study of Rhodiola preparations on behavioral despair of rats". Phytomedicine. 15 (1–2): 84–91. doi:10.1016/j.phymed.2007.10.003. PMID 18054474.

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