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Scientific classification
Domain: Eukaryota
(unranked): Amoebozoa
Class: Discosea
Order: Thecamoebida
Family: Thecamoebidae
Genus: Sappinia

Sappinia is a genus of Amoebozoa.[1] Species are free-living ameba (a single-celled living organism) found in the environment. There are two known species of Sappinia: Sappinia diploidea and Sappinia pedata. This ameba causes amebic encephalitis, which is an infection of the brain. Worldwide, only one case of amebic encephalitis due to Sappinia infection has been reported.

It includes the species Sappinia diploidea and Sappinia pedata.[2][3][4]


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  2. ^ Brown, M.; Spiegel, F.; Silberman, J. (2007). "Amoeba at attention: phylogenetic affinity of Sappinia pedata". The Journal of eukaryotic microbiology. 54 (6): 511–519. doi:10.1111/j.1550-7408.2007.00292.x. PMID 18070328. 
  3. ^ Qvarnstrom, Y.; Da Silva, A.; Schuster, F.; Gelman, B.; Visvesvara, G. (2009). "Molecular confirmation of Sappinia pedata as a causative agent of amoebic encephalitis". The Journal of Infectious Diseases. 199 (8): 1139–1142. doi:10.1086/597473. PMID 19302010. 
  4. ^ Wylezich, C.; Walochnik, J.; Michel, R. (2009). "High genetic diversity of Sappinia-like strains (Amoebozoa, Thecamoebidae) revealed by SSU rRNA investigations". Parasitology research. 105 (3): 869–873. doi:10.1007/s00436-009-1482-1. PMID 19495795.