Sirohydrochlorin

Sirohydrochlorin

Identifiers
CAS Number	1976-85-8 Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:18023
ChemSpider	16736728
KEGG	C05778
PubChem CID	196427
InChI InChI=1S/C42H46N4O16/c1-41(17-39(59)60)23(5-9-35(51)52)29-14-27-21(11-37(55)56)19(3-7-33(47)48)25(43-27)13-26-20(4-8-34(49)50)22(12-38(57)58)28(44-26)15-31-42(2,18-40(61)62)24(6-10-36(53)54)30(46-31)16-32(41)45-29/h13-16,23-24,43-44H,3-12,17-18H2,1-2H3,(H,47,48)(H,49,50)(H,51,52)(H,53,54)(H,55,56)(H,57,58)(H,59,60)(H,61,62)/t23-,24-,41+,42+/m1/s1 Key: AVBHZKNQGDKVEA-ZTKUHGNGSA-N
SMILES C[C@@]1([C@@H](C2=NC1=CC3=NC(=CC4=C(C(=C(N4)C=C5C(=C(C(=C2)N5)CC(=O)O)CCC(=O)O)CCC(=O)O)CC(=O)O)[C@@]([C@@H]3CCC(=O)O)(C)CC(=O)O)CCC(=O)O)CC(=O)O
Properties
Chemical formula	C42H46N4O16
Appearance	yellow solid
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Sirohydrochlorin (SHC) is a macrocyclic metabolic intermediate in the biosynthesis of corrin, precursor to the tetrapyrrole pigment and cofactor F430. It is a yellow compound. Its biosynthetic precursor is dihydrosirohydrochlorin, which in turn is derived from uroporphyrinogen III. It is also the precursor to the siroheme, the prosthetic group in an sulfite reductase.

See also

• Sirohydrochlorin ferrochelatase an enzyme that catalyzes insertion of iron to form siroheme.
• Sirohydrochlorin cobaltochelatase an enzyme that catalyzes insertion of cobalt.