TAF9B

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TAF9B
Identifiers
Aliases TAF9B, DN-7, DN7, TAF9L, TAFII31L, TFIID-31, TATA-box binding protein associated factor 9b
External IDs MGI: 3039562 HomoloGene: 47969 GeneCards: TAF9B
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_015975

NM_001001176
NM_001167988

RefSeq (protein)

NP_057059

NP_001001176.2
NP_001161460.1
NP_001001176
NP_001161460

Location (UCSC) Chr X: 78.13 – 78.14 Mb Chr X: 106.21 – 106.22 Mb
PubMed search [1] [2]
Wikidata
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Transcription initiation factor TFIID subunit 9B is a protein that in humans is encoded by the TAF9B gene.[3][4]

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that is similar to one of the small subunits of TFIID, TBP-associated factor 9, and is also a subunit of TFIID. TAF9 and TAF9b share some functions but also have distinct roles in the transcriptional regulatory process.[4]

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