TCF20

TCF20
Identifiers
Aliases	TCF20, AR1, SPBP, TCF-20, transcription factor 20 (AR1), transcription factor 20, DDVIBA
External IDs	OMIM: 603107; MGI: 108399; HomoloGene: 4131; GeneCards: TCF20; OMA:TCF20 - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	42,343,616 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	82,872,073 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; bone marrow cells; ; islet of Langerhans; ; tonsil; ; mucosa of esophagus; ; blood; ; granulocyte; ; lymph node; ; olfactory zone of nasal mucosa; ; superior frontal gyrus;
	Top expressed in
	Rostral migratory stream; ; genital tubercle; ; tail of embryo; ; dentate gyrus of hippocampal formation granule cell; ; secondary oocyte; ; olfactory tubercle; ; ciliary body; ; dorsal striatum; ; conjunctival fornix; ; supraoptic nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; transcription coactivator activity; metal ion binding; RNA binding; DNA-binding transcription factor activity; protein binding;
Cellular component	nucleoplasm; nuclear body; nucleus;
Biological process	regulation of transcription, DNA-templated; transcription, DNA-templated; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	6942
	21411
ENSG00000283681; ENSG00000281897; ENSG00000262024; ENSG00000282892; ENSG00000283026;
	ENSG00000280467; ENSG00000100207; ENSG00000276461
	ENSMUSG00000041852
	Q9UGU0
	Q9EPQ8
	NM_005650; NM_181492; NM_001378418
	NM_001114140; NM_013836
	NP_005641; NP_852469; NP_001365347
	NP_001107612; NP_038864; NP_001389767
	Wikidata
View/Edit Human	View/Edit Mouse

Transcription factor 20 is a protein that in humans is encoded by the TCF20 gene.^[5]^[6]^[7]

Template:PBB Summary

Interactions

TCF20 has been shown to interact with RNF4.^[8]

References

^ ^a ^b ^c ENSG00000281897, ENSG00000262024, ENSG00000282892, ENSG00000283026, ENSG00000280467, ENSG00000100207, ENSG00000276461 GRCh38: Ensembl release 89: ENSG00000283681, ENSG00000281897, ENSG00000262024, ENSG00000282892, ENSG00000283026, ENSG00000280467, ENSG00000100207, ENSG00000276461 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000041852 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Rajadhyaksha A, Riviere M, Van Vooren P, Szpirer J, Szpirer C, Babin J, Bina M (October 1998). "Assignment of AR1, transcription factor 20 (TCF20), to human chromosome 22q13.3 with somatic cell hybrids and in situ hybridization". Cytogenet Cell Genet. 81 (3–4): 176–7. doi:10.1159/000015021. PMID 9730594.
^ Rekdal C, Sjottem E, Johansen T (January 2001). "The nuclear factor SPBP contains different functional domains and stimulates the activity of various transcriptional activators". J Biol Chem. 275 (51): 40288–300. doi:10.1074/jbc.M006978200. PMID 10995766.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ "Entrez Gene: TCF20 transcription factor 20 (AR1)".
^ Lyngsø, C; Bouteiller G; Damgaard C K; Ryom D; Sanchez-Muñoz S; Nørby P L; Bonven B J; Jørgensen P (August 2000). "Interaction between the transcription factor SPBP and the positive cofactor RNF4. An interplay between protein binding zinc fingers". J. Biol. Chem. 275 (34). UNITED STATES: 26144–9. doi:10.1074/jbc.M003405200. ISSN 0021-9258. PMID 10849425. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help)CS1 maint: unflagged free DOI (link)

Interactions

References

Further reading