TCTN3

TCTN3
Identifiers
Aliases	TCTN3, C10orf61, JBTS18, OFD4, TECT3, tectonic family member 3
External IDs	OMIM: 613847; MGI: 1914840; HomoloGene: 9221; GeneCards: TCTN3; OMA:TCTN3 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	95,694,143 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	40,600,677 bp
RNA expression pattern
	Top expressed in
	corpus epididymis; ; stromal cell of endometrium; ; islet of Langerhans; ; caput epididymis; ; right lobe of thyroid gland; ; pancreatic ductal cell; ; left lobe of thyroid gland; ; gallbladder; ; rectum; ; parotid gland;
	Top expressed in
	fourth ventricle; ; spermatocyte; ; saccule; ; spermatid; ; islet of Langerhans; ; visual cortex; ; otic placode; ; seminiferous tubule; ; medullary collecting duct; ; superior frontal gyrus;
	More reference expression data
	n/a
Orthologs
	26123
	67590
	ENSG00000119977
	ENSMUSG00000025008
	Q6NUS6
	Q8R2Q6
	NM_001143973; NM_015631
	NM_026260; NM_001365072
	NP_001137445; NP_056446
	NP_080536; NP_001352001
	Wikidata
View/Edit Human	View/Edit Mouse

Tectonic family member 3 is a protein in humans that is encoded by the TCTN3 gene. ^[5]

This gene encodes a member of the tectonic gene family which functions in Hedgehog signal transduction and development of the neural tube. Mutations in this gene have been associated with Orofaciodigital Syndrome IV and Joubert Syndrom 18. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2012].

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000119977 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000025008 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Tectonic family member 3". Retrieved 2012-12-22.

References

Further reading