TGM3

TGM3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1L9M, 1L9N, 1NUD, 1NUF, 1NUG
Identifiers
Aliases	TGM3, TGE, transglutaminase 3, UHS2
External IDs	OMIM: 600238; MGI: 98732; HomoloGene: 20690; GeneCards: TGM3; OMA:TGM3 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	2,341,079 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	129,892,319 bp
RNA expression pattern
	Top expressed in
	skin of leg; ; skin of abdomen; ; right uterine tube; ; tonsil; ; minor salivary glands; ; vagina; ; ectocervix; ; gallbladder; ; blood; ; granulocyte;
	Top expressed in
	esophagus; ; left colon; ; lip; ; superior surface of tongue; ; granulocyte; ; hair follicle; ; skin of back; ; skin of abdomen; ; trachea; ; pretectal area;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	metal ion binding; calcium ion binding; catalytic activity; protein-glutamine gamma-glutamyltransferase activity; transferase activity; acyltransferase activity;
Cellular component	extrinsic component of cytoplasmic side of plasma membrane; extracellular exosome; cytoplasm;
Biological process	keratinization; protein tetramerization; hair follicle morphogenesis; cell envelope organization; peptide cross-linking; keratinocyte differentiation;
	Sources:Amigo / QuickGO
Orthologs
	7053
	21818
	ENSG00000125780
	ENSMUSG00000027401
	Q08188
	Q08189
	NM_003245
	NM_009374
	NP_003236
	NP_033400
	Wikidata
View/Edit Human	View/Edit Mouse

For the Tetris game, see Tetris: The Grand Master.

Protein-glutamine gamma-glutamyltransferase E is an enzyme that in humans is encoded by the TGM3 gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000125780 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000027401 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Wang M, Kim IG, Steinert PM, McBride OW (Mar 1995). "Assignment of the human transglutaminase 2 (TGM2) and transglutaminase 3 (TGM3) genes to chromosome 20q11.2". Genomics. 23 (3): 721–2. doi:10.1006/geno.1994.1571. PMID 7851911.
^ Aeschlimann D, Koeller MK, Allen-Hoffmann BL, Mosher DF (Mar 1998). "Isolation of a cDNA encoding a novel member of the transglutaminase gene family from human keratinocytes. Detection and identification of transglutaminase gene products based on reverse transcription-polymerase chain reaction with degenerate primers". J Biol Chem. 273 (6): 3452–60. doi:10.1074/jbc.273.6.3452. PMID 9452468.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ "Entrez Gene: TGM3 transglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase)".