TOPORS

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TOPORS
Identifiers
Aliases TOPORS, LUN, P53BP3, RP31, TP53BPL, TOP1 binding arginine/serine rich protein
External IDs MGI: 2146189 HomoloGene: 4237 GeneCards: TOPORS
RNA expression pattern
PBB GE TOPORS 204071 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005802
NM_001195622

NM_134097

RefSeq (protein)

NP_001182551
NP_005793

NP_598858.2
NP_598858

Location (UCSC) Chr 9: 32.54 – 32.55 Mb Chr 4: 40.26 – 40.27 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

E3 ubiquitin-protein ligase Topors is an enzyme that in humans is encoded by the TOPORS gene.[3][4][5][6]


References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Haluska P Jr, Saleem A, Rasheed Z, Ahmed F, Su EW, Liu LF, Rubin EH (Jul 1999). "Interaction between human topoisomerase I and a novel RING finger/arginine-serine protein". Nucleic Acids Res. 27 (12): 2538–44. doi:10.1093/nar/27.12.2538. PMC 148458Freely accessible. PMID 10352183. 
  4. ^ Rasheed ZA, Saleem A, Ravee Y, Pandolfi PP, Rubin EH (Jun 2002). "The topoisomerase I-binding RING protein, topors, is associated with promyelocytic leukemia nuclear bodies". Exp Cell Res. 277 (2): 152–60. doi:10.1006/excr.2002.5550. PMID 12083797. 
  5. ^ Chakarova CF, Papaioannou MG, Khanna H, Lopez I, Waseem N, Shah A, Theis T, Friedman J, Maubaret C, Bujakowska K, Veraitch B, Abd El-Aziz MM, Prescott de Q, Parapuram SK, Bickmore WA, Munro PM, Gal A, Hamel CP, Marigo V, Ponting CP, Wissinger B, Zrenner E, Matter K, Swaroop A, Koenekoop RK, Bhattacharya SS (Oct 2007). "Mutations in TOPORS cause autosomal dominant retinitis pigmentosa with perivascular retinal pigment epithelium atrophy". Am J Hum Genet. 81 (5): 1098–103. doi:10.1086/521953. PMC 2265653Freely accessible. PMID 17924349. 
  6. ^ "Entrez Gene: TOPORS topoisomerase I binding, arginine/serine-rich". 

Further reading[edit]

External links[edit]