TPX2

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TPX2
Protein TPX2 PDB 1ol5.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases TPX2, C20orf1, C20orf2, DIL-2, DIL2, FLS353, GD:C20orf1, HCA519, HCTP4, REPP86, p100, microtubule nucleation factor
External IDs MGI: 1919369 HomoloGene: 8107 GeneCards: TPX2
RNA expression pattern
PBB GE TPX2 210052 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_012112

NM_001141975
NM_001141976
NM_001141977
NM_001141978
NM_028109

RefSeq (protein)

NP_036244

Location (UCSC) Chr 20: 31.74 – 31.8 Mb Chr 2: 152.85 – 152.9 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Targeting protein for Xklp2 is a protein that in humans is encoded by the TPX2 gene.[3][4][5]


Interactions[edit]

TPX2 has been shown to interact with Aurora A kinase [6] and KIF15

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Heidebrecht HJ, Buck F, Steinmann J, Sprenger R, Wacker HH, Parwaresch R (Jul 1997). "p100: a novel proliferation-associated nuclear protein specifically restricted to cell cycle phases S, G2, and M". Blood. 90 (1): 226–33. PMID 9207457. 
  4. ^ Zhang Y, Heidebrecht H, Rott A, Schlegelberger B, Parwaresch R (Jul 1999). "Assignment of human proliferation associated p100 gene (C20orf1) to human chromosome band 20q11.2 by in situ hybridization". Cytogenet Cell Genet. 84 (3–4): 182–3. doi:10.1159/000015251. PMID 10393424. 
  5. ^ "Entrez Gene: TPX2 TPX2, microtubule-associated, homolog (Xenopus laevis)". 
  6. ^ Kufer, Thomas A; Silljé Herman H W; Körner Roman; Gruss Oliver J; Meraldi Patrick; Nigg Erich A (Aug 2002). "Human TPX2 is required for targeting Aurora-A kinase to the spindle". J. Cell Biol. United States. 158 (4): 617–23. doi:10.1083/jcb.200204155. ISSN 0021-9525. PMC 2174010Freely accessible. PMID 12177045. 

Further reading[edit]