TREML1

TREML1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2FRG
Identifiers
Aliases	TREML1, GLTL1825, PRO3438, TLT-1, TLT1, dJ238O23.3, triggering receptor expressed on myeloid cells like 1
External IDs	OMIM: 609714; MGI: 1918576; HomoloGene: 52257; GeneCards: TREML1; OMA:TREML1 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	41,154,347 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	48,674,204 bp
RNA expression pattern
	Top expressed in
	monocyte; ; blood; ; granulocyte; ; spleen; ; appendix; ; C1 segment; ; bone marrow cells; ; lymph node; ; right lung; ; upper lobe of left lung;
	Top expressed in
	bone marrow; ; spleen; ; embryo; ; lobe of liver; ; white adipose tissue; ; morula; ; yolk sac; ; placenta; ; lung; ; heart;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding;
Cellular component	cytoplasm; integral component of membrane; plasma membrane; membrane; cell surface; platelet alpha granule;
Biological process	innate immune response; calcium-mediated signaling; regulation of immune response; platelet activation;
	Sources:Amigo / QuickGO
Orthologs
	340205
	71326
	ENSG00000161911
	ENSMUSG00000023993
	Q86YW5
	Q8K558
	NM_178174; NM_001271807; NM_001271808
	NM_001289451; NM_001289457; NM_027763
	NP_001258736; NP_001258737; NP_835468
	NP_001276380; NP_001276386; NP_082039
	Wikidata
View/Edit Human	View/Edit Mouse

Trem-like transcript 1 protein is a protein that in humans is encoded by the TREML1 gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000161911 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000023993 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Washington AV, Quigley L, McVicar DW (Nov 2002). "Initial characterization of TREM-like transcript (TLT)-1: a putative inhibitory receptor within the TREM cluster". Blood. 100 (10): 3822–4. doi:10.1182/blood-2002-02-0523. PMID 12393607.
^ Allcock RJ, Barrow AD, Forbes S, Beck S, Trowsdale J (Mar 2003). "The human TREM gene cluster at 6p21.1 encodes both activating and inhibitory single IgV domain receptors and includes NKp44". Eur J Immunol. 33 (2): 567–77. doi:10.1002/immu.200310033. PMID 12645956.
^ "Entrez Gene: TREML1 triggering receptor expressed on myeloid cells-like 1".