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TRIM15

From Wikipedia, the free encyclopedia
TRIM15
Identifiers
AliasesTRIM15, RNF93, ZNF178, ZNFB7, tripartite motif containing 15
External IDsMGI: 1916347; HomoloGene: 23819; GeneCards: TRIM15; OMA:TRIM15 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_033229
NM_052812

NM_001024134
NM_001177872

RefSeq (protein)

NP_150232

n/a

Location (UCSC)Chr 6: 30.16 – 30.17 MbChr 17: 37.17 – 37.18 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Tripartite motif-containing protein 15 is a protein that in humans is encoded by the TRIM15 gene.[5][6][7][8]

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. Its function has not been identified. Alternate splicing of this gene results in two transcript variants encoding different isoforms.[8]

References

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  1. ^ a b c ENSG00000227147, ENSG00000233599, ENSG00000204610, ENSG00000224145, ENSG00000235905, ENSG00000137384, ENSG00000235259 GRCh38: Ensembl release 89: ENSG00000235960, ENSG00000227147, ENSG00000233599, ENSG00000204610, ENSG00000224145, ENSG00000235905, ENSG00000137384, ENSG00000235259Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000050747Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Reymond A, Meroni G, Fantozzi A, Merla G, Cairo S, Luzi L, Riganelli D, Zanaria E, Messali S, Cainarca S, Guffanti A, Minucci S, Pelicci PG, Ballabio A (May 2001). "The tripartite motif family identifies cell compartments". EMBO J. 20 (9): 2140–51. doi:10.1093/emboj/20.9.2140. PMC 125245. PMID 11331580.
  6. ^ Goei VL, Parimoo S, Capossela A, Chu TW, Gruen JR (Mar 1994). "Isolation of novel non-HLA gene fragments from the hemochromatosis region (6p21.3) by cDNA hybridization selection". Am J Hum Genet. 54 (2): 244–51. PMC 1918154. PMID 8304341.
  7. ^ Gruen JR, Nalabolu SR, Chu TW, Bowlus C, Fan WF, Goei VL, Wei H, Sivakamasundari R, Liu Y, Xu HX, Parimoo S, Nallur G, Ajioka R, Shukla H, Bray-Ward P, Pan J, Weissman SM (Feb 1997). "A transcription map of the major histocompatibility complex (MHC) class I region". Genomics. 36 (1): 70–85. doi:10.1006/geno.1996.0427. PMID 8812418.
  8. ^ a b "Entrez Gene: TRIM15 tripartite motif-containing 15".

Further reading

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