TRIM55

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TRIM55
Identifiers
Aliases TRIM55, MURF-2, RNF29, muRF2, tripartite motif containing 55
External IDs MGI: 3036269 HomoloGene: 13205 GeneCards: TRIM55
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_033058
NM_184085
NM_184086
NM_184087

NM_001081281

RefSeq (protein)

NP_149047
NP_908973
NP_908974
NP_908975

n/a

Location (UCSC) Chr 8: 66.13 – 66.18 Mb Chr 3: 19.64 – 19.69 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Tripartite motif-containing protein 55 is a protein that in humans is encoded by the TRIM55 gene.[3][4]

The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein associates transiently with microtubules, myosin, and titin during muscle sarcomere assembly. It may act as a transient adaptor and plays a regulatory role in the assembly of sarcomeres. Four alternatively spliced transcript variants encoding distinct isoforms have been described.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Centner T, Yano J, Kimura E, McElhinny AS, Pelin K, Witt CC, Bang ML, Trombitas K, Granzier H, Gregorio CC, Sorimachi H, Labeit S (Mar 2001). "Identification of muscle specific ring finger proteins as potential regulators of the titin kinase domain". J Mol Biol. 306 (4): 717–26. doi:10.1006/jmbi.2001.4448. PMID 11243782. 
  4. ^ a b "Entrez Gene: TRIM55 tripartite motif-containing 55". 

Further reading[edit]