From Wikipedia, the free encyclopedia
Jump to: navigation, search
Protein TRIM9 PDB 2db8.png
Available structures
PDB Ortholog search: PDBe RCSB
Aliases TRIM9, RNF91, SPRING, tripartite motif containing 9
External IDs MGI: 2137354 HomoloGene: 9045 GeneCards: TRIM9
Gene location (Human)
Chromosome 14 (human)
Chr. Chromosome 14 (human)[1]
Chromosome 14 (human)
Genomic location for TRIM9
Genomic location for TRIM9
Band 14q22.1 Start 50,975,262 bp[1]
End 51,096,061 bp[1]
RNA expression pattern
PBB GE TRIM9 209859 at fs.png
More reference expression data
Species Human Mouse
RefSeq (mRNA)


RefSeq (protein)


Location (UCSC) Chr 14: 50.98 – 51.1 Mb Chr 14: 70.24 – 70.35 Mb
PubMed search [3] [4]
View/Edit Human View/Edit Mouse

Tripartite motif-containing protein 9 is a protein that in humans is encoded by the TRIM9 gene.[5][6][7]

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Its function has not been identified. Alternate splicing of this gene generates two transcript variants encoding different isoforms.[7]


TRIM9 has been shown to interact with SNAP-25.[6]


  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000100505 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021071 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Reymond A, Meroni G, Fantozzi A, Merla G, Cairo S, Luzi L, Riganelli D, Zanaria E, Messali S, Cainarca S, Guffanti A, Minucci S, Pelicci PG, Ballabio A (May 2001). "The tripartite motif family identifies cell compartments". EMBO J. 20 (9): 2140–51. doi:10.1093/emboj/20.9.2140. PMC 125245Freely accessible. PMID 11331580. 
  6. ^ a b Li Y, Chin LS, Weigel C, Li L (Oct 2001). "Spring, a novel RING finger protein that regulates synaptic vesicle exocytosis". J Biol Chem. 276 (44): 40824–33. doi:10.1074/jbc.M106141200. PMID 11524423. 
  7. ^ a b "Entrez Gene: TRIM9 tripartite motif-containing 9". 

Further reading[edit]