TTC1

TTC1
Identifiers
Aliases	TTC1, TPR1, tetratricopeptide repeat domain 1
External IDs	OMIM: 601963; MGI: 1914077; HomoloGene: 2485; GeneCards: TTC1; OMA:TTC1 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	160,065,543 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	43,638,835 bp
RNA expression pattern
	Top expressed in
	apex of heart; ; Achilles tendon; ; cingulate gyrus; ; left ventricle; ; anterior cingulate cortex; ; right frontal lobe; ; C1 segment; ; Brodmann area 9; ; prefrontal cortex; ; islet of Langerhans;
	Top expressed in
	blastocyst; ; genital tubercle; ; tail of embryo; ; morula; ; spermatocyte; ; spermatid; ; secondary oocyte; ; muscle of thigh; ; zygote; ; yolk sac;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	unfolded protein binding; protein binding;
Cellular component	peroxisomal membrane; cytosol;
Biological process	protein folding;
	Sources:Amigo / QuickGO
Orthologs
	7265
	66827
	ENSG00000113312
	ENSMUSG00000041278
	Q99614
	Q91Z38
	NM_003314; NM_001282500
	NM_133795
	NP_001269429; NP_003305
	NP_598556
	Wikidata
View/Edit Human	View/Edit Mouse

Tetratricopeptide repeat protein 1 is a protein that in humans is encoded by the TTC1 gene.^[5]^[6] Template:PBB Summary

Interactions

TTC1 has been shown to interact with HSPA4.^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000113312 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000041278 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Murthy AE, Bernards A, Church D, Wasmuth J, Gusella JF (Nov 1996). "Identification and characterization of two novel tetratricopeptide repeat-containing genes". DNA Cell Biol. 15 (9): 727–35. doi:10.1089/dna.1996.15.727. PMID 8836031.
^ "Entrez Gene: TTC1 tetratricopeptide repeat domain 1".
^ Oh, Won-Kyung; Song Jaewhan (Aug 2003). "Cooperative interaction of Hsp40 and TPR1 with Hsp70 reverses Hsp70-HspBp1 complex formation". Mol. Cells. 16 (1). Korea (South): 84–91. ISSN 1016-8478. PMID 14503850. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysummary=, and |laysource= (help)