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are really not CNS depressants- and many are actually CNS stimulants- but due to secondary activities as DARIs. PCP and PCE come to mind. (talk) 00:40, 15 July 2008 (UTC)Hammilton


Several sentences was distorted by vandalism. Such as: "and are consiSDAWEdfdered to be their functional opposit4t4tes." Fixing it now. Thγmφ (talk) 17:57, 30 September 2009 (UTC)


Shouldn't the "GABA" at the end of the first paragraph read "GABA"? Also, the link takes you to Game Boy Advance, which is completely irrelevant. —Preceding unsigned comment added by Hessammehr (talkcontribs) 16:15, 5 December 2009 (UTC)

sexual arousal and depressants[edit]

Is sexual arousal, as the term suggests, also something usually reduced by depressants and increased by stimulants (I would think there is a distinction here to mere penile erection)? Is alcohol an exception, or is it the rule, or are the effects attributed to it (loss of sexual inhibition and sexual arousal, but also ED) mythical?

I don't think this is entirely irrelevant, even if the paragraph added to the article would state that there appears to be no correlation between "up"/"down"ness and effects on sexual arousal on the one hand and erectile difficulty on the other. There certainly is a massive amount of folklore about the sexual effects of cocaine, methamphetamine, antidepressants, antipsychotics, alcohol; I'm not sure about tobacco and caffeine.

Put in a mathematicians' words, maybe what we're attempting here is projecting a multidimensional set of drugs onto just one or two axes: the depressant-stimulant axis and the axis of sexual arousal are unlikely to be entirely orthogonal, but it's possible drugs fall in all four quadrants: sexually arousing stimulants, sexually arousing depressants, antisexual stimulants, antisexual depressants. (talk) 12:59, 1 July 2010 (UTC)

dissociation, depersonalisation, and depressants[edit]

I'm a bit surprised dissociation is included as an effect of depressants here. The article at depersonalisation is quite clearly in correlating the effect with anxiety, which does appear to contradict anxiolysis being also included as a depressant effect.

Do we have a good external source for that apparent contradiction? (talk) 13:06, 1 July 2010 (UTC)

vs "sedatives"?[edit]

seems to mostly overlap? or they are the same?


sources like this one don't seem to distinguish them? but it's not clear? — Preceding unsigned comment added by (talk) 06:14, 20 December 2011 (UTC)