Talk:Diamine oxidase

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Add redirect from histaminase?

Histaminase does not currently exist, but could someone with more know-how than I please add it and redirect here? Ibrmrn (talk) 19:32, 14 June 2009 (UTC)[reply]

Done. Rich Farmbrough, 23:40, 23 February 2012 (UTC).[reply]

Disputed

The section titled "Reaction catalyzed by DAO" has inconsistencies. It refers to "imidazole-4-acetic acid" and "1,4–metil-imidazolacetic acid" as synonyms, but they are two different chemical compounds. They differ by the presence of a methyl group. If imidazole-4-acetic acid is indeed the product of the described reaction and is also the chemical tested for in the 24-hour urine sample test, then the chemical name "imidazole-4-acetic acid" should be used throughout the paragraph. If the 24-hour urine sample test actually tests for "1,4–metil-imidazolacetic acid" instead, then the text needs to describe how imidazole-4-acetic acid is converted to 1,4–metil-imidazolacetic acid (or how they are otherwise related). Marbletan (talk) 20:43, 20 August 2024 (UTC)[reply]

You are correct, sorry. Could you please fix that section? Maxim Masiutin (talk) 11:23, 22 August 2024 (UTC)[reply]

I've had a closer look and I think it's even more complicated than I thought. The 24 hour test seems to involve neither imidazole-4-acetic acid nor 1,4–metil-imidazolacetic acid, but rather a different metabolite. See here, for example, which describes a 24-hour urine test for 5-hydroxyindoleacetic acid (5-HIAA). I'm not sure I could fix the text in that section without doing a lot of research first. Perhaps it is best to remove the section for now? Marbletan (talk) 12:41, 22 August 2024 (UTC)[reply]

Please consider keeping the information that Acid 1,4–metil-imidazolacetic is a metabolite of histamine with diagnostic value.

I found the following references to back up this claim, but I don't have access to the information from them:

Florence Ida Hsu, Joshua A Boyce. Biology of Mast Cells and their Mediators. In Middleton’s Allergy, Seventh Edition., Mosby Elsevier, 2009, 320.
J. Andrew Grant, Saffana N. Hassan, Patricia A. Leonard. Mast Cell and Basophil-derived Mediators. In Atlas Of Allergic Diseases, 2nd Edition, Current Medicine LLC, 19.
Karin Hartmann, Stefanie B Bruns and Beate M Henz. Mastocytosis: Review of Clinical and Experimental Aspects. In Journal of Investigative Dermatology Symposium Proceedings (2001) 6, 143–147.
Luigi Santacroce. Malignant Carcinoid Syndrome: Differential Diagnoses & Workup. emedicine.escape.com. Reference Type: Internet Communication.
Philip L Lieberman. Anaphylaxis. In Middleton’s Allergy, Seventh Edition., Mosby Elsevier, 2009, 1041.
Robert Hamilton, Anne Kagey-Sobotka. In Vitro Diagnostic Tests of IgE-Mediated Diseases. In Diagnostic Testing of Allergic Diseases, Marcel Dekker Inc, 2000, 99-100.

I took these references from a website of a lab at https://www.synevo.md/shop/acid-14-metil-imidazolacetic-metabolit-histamina/

You can use a translation tool to translate from Romanian into English.

I guess for now it is better for us to find CAS or PubChem ID numbers for both compounds.

Unfortunately, scientific publications rarely have them.

Therefore, in a scientific paper (a review) we with my coauthor made a table to uniquely identify all compounds, see http://doi.org/10.15347/wjm/2023.003 -- there is a subsection "Abbreviations and Identifiers".

You are right that we should avoid using them as synonyms.

Let me do these edits. Maxim Masiutin (talk) 20:27, 23 August 2024 (UTC)[reply]

If you no longer dispute the content with that information moved, please consider removing the banner :-) Maxim Masiutin (talk) 20:40, 23 August 2024 (UTC)[reply]

I have removed the "disputed" template because I fullfilled your request and removed the text which was the source of the dispute. Maxim Masiutin (talk) 12:46, 1 September 2024 (UTC)[reply]