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Is lesioning a medical use?
I understand Medicine to be a science that cures illnesses; how can it be that causing lesions to the brain is listed as a medical use? What can you cure by destroying brain-cells? Thanks for answering this question.
MiG-25 12:27, 18 April 2007 (UTC)
Ibotenic acid is an unstable compound and decarboxylates into muscimol. The Ibotenic acid is most concentrated under the amanita muscaria's red skin.
I can understand why it is tempting to compare the effects of ibotenic acid and muscimol to zolpidem and other z-drugs, since both act on the GABA-system. nevertheless, it doesn't work out, since there are significant pharmacological differences: zolpidem (and other z-drugs) act as GABA receptor modulators, just in the same way as benzodiazepines do. muscimol, on the other hand, is a direct agonist on the GABA receptor. and if this subtile scientific difference doesn't convince you: I have extensive experience with the psychoactive use of both zolpidem and amanita muscaria mushrooms, and I can assure you that they are not alike at all. zolpidem produces an alcohole-like intoxication with pronounced memory loss, which is only occasionally accompanied by slight hallucinations. amanita muscaria, on the other hand, is an extremely potent entheogen, which produces profound changes in the perception of time, space and self. IMHO it is one of the most profound psychedelics there is, which compares in no way with the dull intoxication zoplidem provides. --Diogenes2000 (talk) 00:20, 24 August 2012 (UTC)
Revisions as part of chemistry project
The recent revisions to the article were part of an assignment for a chemistry course (The Chemistry of Poisons, I am the instructor). The student is working on further improving the quality of the article based on the notes in the revision history, which were helpful and appreciated. I am posting to put the revisions in context, and clarify the focus on chemistry. Hopefully consensus can be reached on what topics are appropriate to include in the article. Ajfrontier (talk) 23:24, 4 May 2015 (UTC)