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ketones in diabetes[edit]

What about pokemon? — Preceding unsigned comment added by (talk) 02:44, 11 December 2014 (UTC) Ketones are also a product of body chemistry when the body is under stress. In diabetics, after a sustained period in hypergleacemia (too much sugar in the blood), ketones present in the urine are evidence of advanced disease status.

As noted in the article, diabetic ketoacidosis, this occurs because of prolonged inadequacy of insulin effect rather than "sustained hyperglycemia". alteripse 23:07, 27 May 2006 (UTC)

This needs some solid chemistry attached to it. Something like "In the absence of insulin to convert glucose to energy, mitochondrial cells burn fat cells. This incomplete oxidation results in ketone production. Diabetic ketoacidosis, a potentially deadly condition, results in organ damage from ketones in the bloodstream." There should be many references available, perhaps in Wikipedia, that describe this chemistry. — Preceding unsigned comment added by (talk) 15:00, 28 October 2015 (UTC)

secondary alcohols to ketone[edit]

the oxidation of secondary alcohols to ketones does not require strong oxidizing agents. it can be achieved (and in the laboratory, is almost always achieved) with extremely mild reagents. Two common examples are the Dess-Martin oxidation with DMP (Dess-Martin Periodinane) and the Swern Oxidation (Oxalyl Chloride and DMSO).

Agreed. I have greatly revised the synthesis section and included these methods, among others. shultzc (talk) 11:50, 27 November 2008 (UTC)


Guidance on pronounciation should follow IPA. —DIV ( (talk) 09:03, 10 April 2008 (UTC))

Done. (talk) 03:30, 9 February 2009 (UTC)

ketones and aldehydes[edit]

Ketones and aldehydes both have a carbonyl group. Why is the difference between them, apart from the carbonyl group being attached to a primary or a secondary carbon? Received the following question today: why is it propanal, in stead of 1-propanone? Could anyone elaborate on the difference between aldehydes and ketones? —Preceding unsigned comment added by (talk) 13:44, 2 March 2010 (UTC)

origin of the name "keton"[edit]

"and in fact the word ketone derives its name from Aketon, the German word for acetone.[2]"

This seems to be false information, I couldn't find Aketon as a German word in the "Duden" [], the most comprehensive dictionary of the German languages. Several dictionary books I own and online dictionaries like the German Wiktionary [1] gave no result, either. In Germany we use "Aceton"(sientific) or "Azeton" - the c resp. z are pronounced as (a-TZ-eton), [2]has an example. (talk) 13:53, 19 May 2010 (UTC)

ketones and esters[edit]

this page mixes up ketones and esters rather frequently. in one section, it says that ketones are distinct from esters, and in other sections, the carboxyl group of esters are highlighted as examples of ketones.

for the record, esters and ketones are not the same, and should be treated differently. — Preceding unsigned comment added by (talk) 04:11, 19 November 2012 (UTC)

Well I dont see a problem, could you be more specific?--Smokefoot (talk) 13:43, 19 November 2012 (UTC)

Ketones as cellular energy source ("preferred"?)[edit]

I've read a few things discussing how the body can use ketone metabolism as an alternative to glucose metabolism - and even claimed by some researchers (Veech in particular) that ketones are preferred by at least some of the body's cells:

Ketosis - Implications from Veech's latest paper - 2012 lay-secondary blog post [[3]]

"Metabolic Effects of the Very-Low-Carbohydrate Diets: Misunderstood "Villains" of Human Metabolism" (2004 [4]

"The therapeutic implications of ketone bodies: the effects of ketone bodies in pathological conditions: ketosis, ketogenic diet, redox states, insulin resistance, and mitochondrial metabolism." (2004) [5]

"Ketoacids? Good medicine?" (2003) [6]

"Ketone bodies, potential therapeutic uses." (2001) [7]

"Medical aspects of ketone body metabolism." (1995) [8]

Should this be mentioned? — Preceding unsigned comment added by Jimw338 (talkcontribs) 00:18, 18 March 2013 (UTC)

A generally nicely done introductory article[edit]

Stopping by after linking keto groups of steroids to this page, and was very pleased to see it in such fine shape. Kudos to the team keeping it chemically/technically, "encyclopedically", and stylistically spot on. Bravi. Le Prof Leprof 7272 (talk) 01:15, 21 June 2014 (UTC)

Will have a whack at the lede[edit]

after discovering the following sentence about the carbonyl being "simple":

  • "They are considered "simple" because they don't have reactive groups like -OH or -Cl attached directly to the carbon atom in the carbonyl group, as in carboxylic acids containing -COOH."

This is a concept I have never come across in a couple of decades of university organic teaching and research, which appears to have been a stray addition rather closely "paraphrased" from this web content:

  • "They are simple in the sense that they don't have other reactive groups like -OH or -Cl attached directly to the carbon atom in the carbonyl group - as you might find, for example, in carboxylic acids containing -COOH." See REF, [9]

Bottom line, it is not solid encyclopedic content—not acceptable in near quoting the source, or in its URL-only citation, or in the entry level (sixth form at best) nature of this nice, but too basic web content. (With Clayden's OChem, why ever cite such as this?) So, it will be replaced once I have time. Le Prof Leprof 7272 (talk) 04:07, 21 June 2014 (UTC)

If my mind serves me[edit]

here are some ketone-containing drugs: acetohexamide, befunolol, daunorubicin, ethacrynic acid, haloperidol, ketoprofen, metyrapone, loxoprofen, naloxone, and naltrexone. Le Prof Leprof 7272 (talk) 04:27, 21 June 2014 (UTC)