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List of drugs

As of 2012, 13 drugs with liposomal delivery systems have been approved and five additional liposomal drugs were in clinical trials.[citation needed]

List of clinically approved liposomal drugs

Name Trade name Company Indication Liposomal Excipients
Liposomal amphotericin B Abelcet Enzon Fungal infections DMPC and DMPG
Liposomal amphotericin B Ambisome Gilead Sciences Fungal and protozoal infections HSPC, Cholesterol, DSPG
Liposomal cytarabine Depocyt Pacira (formerly SkyePharma) Malignant lymphomatous meningitis DOPC, Cholesterol, DPPG
Liposome Pro-Liposome base Chemajet Chemical and Pharmaceutical Industries Employ surface ligands for attaching to unhealthy tissue LEC. Phosphatidylcholine
Liposomal daunorubicin DaunoXome Gilead Sciences HIV-related Kaposi’s sarcoma DSPC, Cholesterol
Liposomal doxorubicin Myocet Zeneus Combination therapy with cyclophosphamide in metastatic breast cancer LIPOVA-E120, Cholesterol
Liposomal IRIV vaccine Epaxal Crucell Hepatitis A LECIVA-S70
Liposomal IRIV vaccine Inflexal V Berna Biotech Influenza LECIVA-S90
Liposomal morphine DepoDur SkyePharma, Endo Postsurgical analgesia DOPC, Cholesterol, DPPG
Liposomal verteporfin Visudyne QLT, Novartis Age-related macular degeneration, pathologic myopia, ocular histoplasmosis Egg PG, DMPC
Liposome-proteins SP-B and SP-C Curosurf Chiesi Farmaceutici, S.p.A. pulmonary surfactant for Respiratory Distress Syndrome (RDS) Leciva-S90
Liposome-PEG doxorubicin Doxil/Caelyx Ortho Biotech, Schering-Plough HIV-related Kaposi’s sarcoma, metastatic breast cancer, metastatic ovarian cancer MPEG-DSPE, HSPC, Cholesterol
Micellular estradiol Estrasorb Novavax Menopausal therapy Soybean oil, Polysorbate80
Liposomal vincristine Marqibo Spectrum Pharmaceuticals Acute Lymphoblastic Leukemia (ALL) and Melanoma Cholesterol and egg sphingomyelin
Liposome-PEG doxorubicin Lipo-Dox TTY BIOPHARM HIV-related Kaposi’s sarcoma, metastatic breast cancer, metastatic ovarian cancer, Multiple Myeloma MPEG-DSPE, DSPC, Cholesterol

--Jytdog (talk) 23:23, 28 January 2017 (UTC)