Talk:Pistol ribozyme
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deleted text Oct 30, 2018
[edit]I deleted the following text:
- In 2015, Breaker et al, discovered that the gene sequence coding for twister and hammerhead ribozymes are located very closely to each other. They suggested that the sequence coding for other ribozyme might be located within the vicinity. Out of the sixteen ribozyme sequences discovered,only three possess self-cleaving properties. These three sequences were determined to belong to new three classes of ribozymes, sister twister, hatchet, and pistol.[1]
This text has numerous mistakes, e.g., (1) the discovery that twister & hammerhead ribozymes are located closely to each other was made in a 2013 paper by the same group, not the 2015 paper, (2) gene sequences do not "code" for RNAs, (3) within what "vacinity", (4) also protein-coding genes associated with self-cleaving ribozymes are not mentioned, (4) "sixteen ribozyme sequences discovered": there were 16 _candidate_ ribozyme _classes_ reported in the 2015 paper, most of them do not appear to be ribozymes, and it was far more than 16 sequences, (5) similar problem confusing "sequences" and "classes" in the last sentence.
Moreover, this bioinformatics procedure is already described in the RAGATH RNA motifs, a link to which I've already added.