Tetrahydropapaveroline
Appearance
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Names | |
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IUPAC name
1-[(3,4-dihydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol
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Other names
Norlaudanosoline; Tetrahydroxypapaveroline
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Identifiers | |
3D model (JSmol)
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ECHA InfoCard | 100.158.898 |
PubChem CID
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CompTox Dashboard (EPA)
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Properties | |
C16H17NO4 | |
Molar mass | 287.315 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Tetrahydropapaveroline (norlaudanosoline) is a benzyltetrahydroisoquinoline alkaloid.[1]
It can be formed in trace amounts in the brain by a condensation reaction of dopamine and dopaldehyde (a metabolite of dopamine).[1][2]
It inhibits dopamine uptake within the cerebral cortex.[citation needed]
References
- ^ a b Richter, Derek. Addiction and Brain Damage. Routledge. p. 24. ISBN 9781315454030.
- ^ "Alcohol drinking: abnormal intake caused by tetrahydropapaveroline in brain". Science. 196 (4289): 554–556. 29 Apr 1977. doi:10.1126/science.557839.
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