USP2

USP2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2HD5, 2IBI, 3NHE, 3V6C, 3V6E
Identifiers
Aliases	USP2, UBP41, USP9, ubiquitin specific peptidase 2
External IDs	OMIM: 604725; MGI: 1858178; HomoloGene: 3098; GeneCards: USP2; OMA:USP2 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	119,381,711 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	44,095,627 bp
RNA expression pattern
	Top expressed in
	muscle of thigh; ; gastrocnemius muscle; ; left testis; ; sperm; ; apex of heart; ; right testis; ; secondary oocyte; ; Skeletal muscle tissue of rectus abdominis; ; left ventricle; ; right auricle;
	Top expressed in
	seminiferous tubule; ; plantaris muscle; ; muscle of thigh; ; extensor digitorum longus muscle; ; skeletal muscle tissue; ; vestibular membrane of cochlear duct; ; neural layer of retina; ; gastrocnemius muscle; ; ankle; ; soleus muscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	cysteine-type peptidase activity; metal ion binding; peptidase activity; protein binding; identical protein binding; cysteine-type endopeptidase activity; hydrolase activity; ubiquitin protein ligase binding; cyclin binding; thiol-dependent deubiquitinase;
Cellular component	cytoplasm; centrosome; cell cortex; perinuclear region of cytoplasm; nucleus; nucleoplasm; membrane;
Biological process	ubiquitin-dependent protein catabolic process; rhythmic process; muscle organ development; protein stabilization; positive regulation of mitotic cell cycle; negative regulation of transcription by RNA polymerase II; circadian regulation of gene expression; proteolysis; circadian behavior; cell cycle; entrainment of circadian clock by photoperiod; locomotor rhythm; protein deubiquitination;
	Sources:Amigo / QuickGO
Orthologs
	9099
	53376
	ENSG00000036672
	ENSMUSG00000032010
	O75604
	O88623
	NM_001243759; NM_004205; NM_171997
	NM_016808; NM_198091; NM_198092
	NP_001230688; NP_004196; NP_741994
NP_058088; NP_932759; NP_932760; NP_001394747; NP_001394748;
	NP_001394749; NP_001394750; NP_001394751; NP_001394752; NP_001394753; NP_001394754; NP_001394755; NP_001394756
	Wikidata
View/Edit Human	View/Edit Mouse

Ubiquitin carboxyl-terminal hydrolase 2 is an enzyme that in humans is encoded by the USP2 gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000036672 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000032010 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Puente XS, Sanchez LM, Overall CM, Lopez-Otin C (Jul 2003). "Human and mouse proteases: a comparative genomic approach". Nat Rev Genet. 4 (7): 544–58. doi:10.1038/nrg1111. PMID 12838346.
^ "Entrez Gene: USP2 ubiquitin specific peptidase 2".

References

Further reading