UXS1

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UXS1
Protein UXS1 PDB 2b69.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases UXS1, SDR6E1, UGD, UDP-glucuronate decarboxylase 1
External IDs MGI: 1915133 HomoloGene: 41609 GeneCards: UXS1
Gene location (Human)
Chromosome 2 (human)
Chr. Chromosome 2 (human)[1]
Chromosome 2 (human)
Genomic location for UXS1
Genomic location for UXS1
Band No data available Start 106,093,303 bp[1]
End 106,194,339 bp[1]
RNA expression pattern
PBB GE UXS1 219675 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001253875
NM_001253876
NM_025076

NM_026430

RefSeq (protein)

NP_001240804
NP_001240805
NP_079352

NP_080706

Location (UCSC) Chr 2: 106.09 – 106.19 Mb Chr 2: 43.75 – 43.83 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

UDP-glucuronic acid decarboxylase 1 is an enzyme that in humans is encoded by the UXS1 gene.[5][6]

UDP-glucuronate decarboxylase (UGD; EC 4.1.1.35) catalyzes the formation of UDP-xylose from UDP-glucuronate. UDP-xylose is then used to initiate glycosaminoglycan biosynthesis on the core protein of proteoglycans.[supplied by OMIM][6]

See also[edit]


References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000115652 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000057363 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Persson B, Kallberg Y, Bray JE, Bruford E, Dellaporta SL, Favia AD, Duarte RG, Jornvall H, Kavanagh KL, Kedishvili N, Kisiela M, Maser E, Mindnich R, Orchard S, Penning TM, Thornton JM, Adamski J, Oppermann U (Feb 2009). "The SDR (Short-Chain Dehydrogenase/Reductase and Related Enzymes) Nomenclature Initiative". Chem Biol Interact. 178 (1–3): 94–8. PMC 2896744Freely accessible. PMID 19027726. doi:10.1016/j.cbi.2008.10.040. 
  6. ^ a b "Entrez Gene: UXS1 UDP-glucuronate decarboxylase 1". 

Further reading[edit]