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UXS1

From Wikipedia, the free encyclopedia
UXS1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesUXS1, SDR6E1, UGD, UDP-glucuronate decarboxylase 1
External IDsOMIM: 609749; MGI: 1915133; HomoloGene: 41609; GeneCards: UXS1; OMA:UXS1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_026430

RefSeq (protein)

NP_080706
NP_001355216
NP_001355217
NP_001355218

Location (UCSC)Chr 2: 106.09 – 106.19 MbChr 1: 43.75 – 43.83 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

UDP-glucuronic acid decarboxylase 1 is an enzyme that in humans is encoded by the UXS1 gene.[5][6]

UDP-glucuronate decarboxylase (UGD; EC 4.1.1.35) catalyzes the formation of UDP-xylose from UDP-glucuronate. UDP-xylose is then used to initiate glycosaminoglycan biosynthesis on the core protein of proteoglycans.[supplied by OMIM][6]

See also

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References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000115652Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000057363Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Persson B, Kallberg Y, Bray JE, Bruford E, Dellaporta SL, Favia AD, Duarte RG, Jornvall H, Kavanagh KL, Kedishvili N, Kisiela M, Maser E, Mindnich R, Orchard S, Penning TM, Thornton JM, Adamski J, Oppermann U (Feb 2009). "The SDR (Short-Chain Dehydrogenase/Reductase and Related Enzymes) Nomenclature Initiative". Chem Biol Interact. 178 (1–3): 94–8. doi:10.1016/j.cbi.2008.10.040. PMC 2896744. PMID 19027726.
  6. ^ a b "Entrez Gene: UXS1 UDP-glucuronate decarboxylase 1".

Further reading

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