User:Ddander3
Herbert Charles Brown | |
|---|---|
| Born | May 22, 1912 |
| Nationality | USA |
| Alma mater | University of Chicago |
| Known for | Organoboranes |
| Awards | National Medal of Science 1969 Elliott Cresson Medal 1978 |
| Scientific career | |
| Fields | Chemistry |
| Institutions | University of Chicago, Purdue University |
| Doctoral advisor | Hermann Irving Schlesinger |
Arun K. Ghosh
[edit]Arun K. Ghosh is an organic chemist specializing in . Discovered Darunavir based on backbone binding design concept.
Biography
[edit]- 1988-1994 Research Fellow, Merck Research Laboratories, West Point, PA
- 1994-1997 Assistant Professor, Dept. of Chemistry, University of Illinois at Chicago, Chicago, IL
- 1997-1999 Associate Professor, Dept. of Chemistry, University of Illinois at Chicago, Chicago, IL
- 1999-2005 Professor, Dept. of Chemistry, Purdue University, West Lafayette, IN
- 2005-Present Ian P. Rothwell Distinguished Professor, Purdue University, West Lafayette, IN
Education
[edit]He received the following degrees:
- BSc (Honors), Calcutta University, 1978
- MSc, Indian Institute of Technology, Kanpur, 1981
- PhD, University of Pittsburgh, 1985
Following these studies, he went on to become a Post doctoral Fellow under Professor E. J. Corey at Harvard University from 1985-1988.
Major Contributions
[edit]Publications
[edit]Arun K. Ghosh has more than 200 scientific publications [1]
Design of Aspartic Acid Protease Inhibitors
[edit]HIV-1 Protease Inhibitors
[edit]Beta Secretase-1 Inhibitors
[edit]Total Synthesis
[edit]Methodology
[edit]Asymmetric Aldol Reactions
[edit]Multicomponent Reactions
[edit]Awards
[edit]- Arthur C. Cope Scholar Award, 2010 [2]
- IUPAC-Richter Prize, 2010 [3]
- Robert Scarborough Excellence in Medicinal Chemistry Award, 2008 [4]
- Fellow of the American Association for the Advancement of Science, 2005 [5]
- University Scholar, University of Illinois , 1998-2000
- Research Fellow, Merck Research Laboratories, 1988-94
- National Scholar, Government of India, 1976-1981
See Also
[edit]- Medicinal chemistry
- Aspartate protease
- HIV/AIDS
- HIV-1 protease
- Darunavir
- Alzheimer's disease
- Beta-secretase 1
- Multicomponent Reaction
- Aldol Reaction
References
[edit]Further Reading
[edit]- Aspartic Acid Proteases as Therapeutic Targets
- The FDA Approved HIV-1 Protease Inhibitors for Treatment of HIV/AIDS
- Modern Aldol Reactions