User:Mr. Ibrahem/Besifloxacin

Mr. Ibrahem/Besifloxacin
Clinical data
Trade names	Besivance
Other names	Besifloxacin hydrochloride
AHFS/Drugs.com	Monograph
MedlinePlus	a610011
License data	US FDA: Besifloxacin;
Routes of; administration	Ophthalmic
Drug class	Antibiotic (fluoroquinolone)
Legal status
Legal status	US: ℞-only;
Identifiers
	IUPAC name 7-[(3R)-3-Aminoazepam-1-yl]-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid;
Chemical and physical data
Formula	C19H21ClFN3O3
Molar mass	393.84 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Fc1c(c(Cl)c2c(c1)C(=O)C(\C(=O)O)=C/N2C3CC3)N4CCCC[C@@H](N)C4;
	InChI InChI=1S/C19H21ClFN3O3/c20-15-16-12(18(25)13(19(26)27)9-24(16)11-4-5-11)7-14(21)17(15)23-6-2-1-3-10(22)8-23/h7,9-11H,1-6,8,22H2,(H,26,27)/t10-/m1/s1; Key:QFFGVLORLPOAEC-SNVBAGLBSA-N;

Besifloxacin, sold under the brand name Besivance, is an antibiotic used to treat bacterial conjunctivitis.^[2] It is used as an eye drop.^[2]

Common side effects include redness of the eye.^[2] Other side effects may include allergic reactions.^[1] Safety in pregnancy is unclear.^[1] It is a fluoroquinolone and works by blocking DNA topoisomerases.^[1]

Besifloxacin was approved for medical use in the United States in 2009.^[2] In the United States a 5 ml bottle costs about 210 USD as of 2022.^[3]

References[edit]

^ ^a ^b ^c ^d "Besifloxacin Monograph for Professionals". Drugs.com. Archived from the original on 24 January 2021. Retrieved 10 January 2022.
^ ^a ^b ^c ^d ^e ^f "DailyMed - BESIVANCE- besifloxacin suspension". dailymed.nlm.nih.gov. Archived from the original on 24 March 2021. Retrieved 10 January 2022.
^ "Besivance Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 16 August 2021. Retrieved 10 January 2022.