User:Mr. Ibrahem/Tipranavir
Clinical data | |
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Pronunciation | /tɪpˈrænəvɪər/ tip-RAN-ə-veer |
Trade names | Aptivus |
Other names | Tipranavir disodium |
AHFS/Drugs.com | Monograph |
MedlinePlus | a606009 |
License data |
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Pregnancy category |
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Routes of administration | By mouth (soft capsules) |
Drug class | Protease inhibitor (PI)[1] |
Legal status | |
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Pharmacokinetic data | |
Protein binding | 99.9% |
Metabolism | Liver |
Elimination half-life | 4.8–6 hours |
Excretion | Feces (82.3%), urine (4.4%) |
Identifiers | |
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Chemical and physical data | |
Formula | C31H33F3N2O5S |
Molar mass | 602.67 g·mol−1 |
3D model (JSmol) | |
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Tipranavir (TPV), sold under the brand name Aptivus, is a medication used to treat HIV/AIDS in combination with ritonavir among others medications.[1] It is used with similar medications are not effective.[1] It is taken by mouth.[1] It is used in those over the age of two years.[3]
Common side effects include diarrhea, nausea, fever, tiredness, and headache.[1] Other side effects may include intracranial bleeding, liver inflammation, liver failure, high blood sugar, and abnormal lipid levels.[1] It is a protease inhibitor (PI) which blocks HIV protease.[1]
Tipranavir was approved for medical use in the United States and Europe in 2005.[1][3] In the United Kingdom it costs the NHS about £440 a month as of 2021.[4] In the United States this amount costs about 1,800 USD.[5]
References
[edit]- ^ a b c d e f g h i "Tipranavir Monograph for Professionals". Drugs.com. Archived from the original on 26 August 2021. Retrieved 4 October 2021.
- ^ "Aptivus- tipranavir capsule, liquid filled Aptivus- tipranavir solution". DailyMed. 26 June 2020. Archived from the original on 22 October 2021. Retrieved 2 December 2020.
- ^ a b "Aptivus". Archived from the original on 14 April 2021. Retrieved 4 October 2021.
- ^ BNF (80 ed.). BMJ Group and the Pharmaceutical Press. September 2020 – March 2021. p. 697. ISBN 978-0-85711-369-6.
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: CS1 maint: date format (link) - ^ "Aptivus Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 5 August 2016. Retrieved 4 October 2021.