User:Roceras/fxmenopause
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fxMenopause
The fxMenopause dietary supplement is derived from phytoestrogens which act as a Selective Estrogen Receptor Modulator (SERM). The phytoestrogens contained in fxMenopause are from food sources which have been safely consumed by all members of the family for many hundreds of years.
As the name suggests, fxMenopause is suitable for women in their menopause years and beyond who either cannot or do not wish to take medicinal HRT. Given the right intake, first time users are expected to see positive signs within 4 weeks.
Mode of Action[edit]
Phytoestrogens are defined as any plant substance or metabolite that induces biological responses in vertebrates and can mimic or modulate the actions of endogenous oestrogens usually binding to oestrogen receptors. Examples of phytoestrogens include certain fruit, vegetables, nuts and seeds. Phytoestrogens are NOT steroids, but they can still interact with the oestrogen receptors in the body.
In addition, different classes of phytoestrogens can preferentially activate the oestrogen receptors isoforms alpha or beta to a different degree and scientific research suggest this phenomena may support the body in many aspects. This is particularly beneficial for peri and post menopausal women whose own levels of oestrogen have reduced.
The phytoestrogens in fxMenopause have unique SERM activity that preferentially activates the oestrogen receptor beta to a greater extent relative to the oestrogen receptor alpha. The beta receptors are particularly associated with the kidneys, brain bone, heart, lungs, intestinal mucosa, prostate and endothelial cells.
Safety[edit]
Independent safety testing has been conducted on fxMenopause, including acute toxicity, repeat-dose chronic toxicity and mutagenicity tests. The extracts did not cause any clinically significant findings in haematology, blood chemistry, urinalysis or histopathology of systemic targets in the repeat-dose chronic toxicity studies which simulate the effects of long term exposure. In addition in genotoxicity tests, the botanical extracts did not cause any in vivo chromosomal genetic DNA mutation.
Quality[edit]
Production in undertaken in a cGMP certified facility as assessed by NSF International - compliance with NSF/ANSI Standard 173, Section 8 for Dietary Supplements.
Each production batch is tested for heavy metals, toxins, yeasts, moulds and aflotoxins.
Efficacy[edit]
In the 2003 UK study on the effects of fxMenopause on menopausal women, an exposure-response relationship was established. Trial participants recorded an average 50% and 66% baseline reduction in hot flashes or night sweats within 10 days and 3 weeks of consumption of fxMenopause, respectively. The percent reduction is well beyond the 25-30% reduction usually attributed to placebo. Overall, there was a significant improvement of total symptom scores measured using the MRS, RAND 36, PIRS and Facial Skin Questionnaire among the trial participants, leading to an enhanced quality of life.
Trade Names[edit]
fxMenopause
References[edit]
External links[edit]
Category:Menopause Category:Selective estrogen receptor modulators