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Welcome![edit]

Hello, Francesco Galli, and welcome to Wikipedia! Thank you for your contributions. I hope you like the place and decide to stay. Here are a few links to pages you might find helpful:

You may also want to take the Wikipedia Adventure, an interactive tour that will help you learn the basics of editing Wikipedia. You can visit The Teahouse to ask questions or seek help.

Please remember to sign your messages on talk pages by typing four tildes (~~~~); this will automatically insert your username and the date. If you need help, check out Wikipedia:Questions, ask me on my talk page, or ask for help on your talk page, and a volunteer should respond shortly. Again, welcome! Zefr (talk) 16:17, 17 August 2017 (UTC)[reply]

Citing sources for vitamin E and other medical topics[edit]

Please review WP:MEDRS, particularly WP:MEDASSESS, for selecting high-quality sources for vitamin and other medical content. The sources you have introduced are too low in quality to use, remaining mostly as preliminary research. Also review WP:CIT for reference templates and WP:REFPUNCT for where punctuation goes with references, i.e., before the source. You can use Citation bot to fill in reference details for you from PubMed and DOI, explained here. Thanks and good luck. --Zefr (talk) 16:23, 17 August 2017 (UTC)[reply]

Formatting a source[edit]

When editing, look to the upper left of the edit box where you see a dropdown pick list for "Templates". That is where all the fields needed for filling in information from the source can be added, then inserted where your cursor was left in the edit. Be sure to check the "Show preview" function, bottom left of the edit box, to review your edit for accuracy and format. You still are putting punctuation after, rather than before the reference, like this: text, text.Cite error: A <ref> tag is missing the closing </ref> (see the help page)..


Observational and pilot intervention studies have described the efficacy of vitamin E in improving biochemistry and histology features of NAFLD and NASH reviewed in [1], [2].

Two recent randomized vitamin E (800 IU/day for 96 weeks) placebo-controlled multicenter clinical trials with histology biomarkers of inflammation and fibrosis as end points confirmed the therapeutic role of vitamin E in adult non-diabetic and pediatric NASH patients, the PIVENS [3] and TONIC [4] trials, respectively. As a consequence, the 2012 Guidelines of the American Association for the Study of Liver Diseases, have included the daily administration of 800 UI vitamin E among the first line treatments for nondiabetic adults with biopsy-proven NASH [5]. The available evidence on the contrary has not considered sufficient to recommend this treatment to diabetic patients with NASH as well as in NAFLD patients without liver biopsy, NASH cirrhosis, or cryptogenic cirrhosis. The same recommendations have been provided by other hepatology and gastroenterology associations in other regions [6],[7].


Biomaterials and medical devices

Vitamin E (alpha-tocopherol) has been used as a modifier to increase biocompatibility and antioxidant properties of biomaterials and medical devices, such as polymers (UHMWPE) used in hip and knee implants [8] and hemodialysis membranes [9][10].

References

  1. ^ Al-Busafi, S.A.; Bhat, M.; Wong, P.; Ghali, P.; Deschenes, M. (2012). "Antioxidant therapy in nonalcoholic steatohepatitis". Hepat Res Treat. 2012: 947575. doi:10.1155/2012/947575. PMID PMC3512254. {{cite journal}}: Check |pmid= value (help)CS1 maint: unflagged free DOI (link)
  2. ^ Rolo, A.P.; Teodoro, J.S.; Palmeira, C.M. (2012). "Role of oxidative stress in the pathogenesis of nonalcoholic steatohepatitis". Free Radic Biol Med. 52: 59–69. doi:10.1016/j.freeradbiomed.2011.10.003.
  3. ^ Sanyal, A.J.; Chalasani, N.; Kowdley, K. V.; et al. (2010). "Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis". N Engl J Med. 362 (18): 1675–1685. doi:10.1056/NEJMoa0907929. PMID PMC2928471. {{cite journal}}: Check |pmid= value (help); Explicit use of et al. in: |last4= (help)
  4. ^ Lavine, J.E.; Schwimmer, J.B.; Van Natta, M.L.; et al. (2011). "Effect of vitamin E or metformin for treatment of nonalcoholic fatty liver disease in children and adolescents: the TONIC randomized controlled trial". JAMA. 305 (16): 1659–1668. doi:10.1001/jama.2011.520. PMID PMC3110082. {{cite journal}}: Check |pmid= value (help); Explicit use of et al. in: |last4= (help)
  5. ^ Chalasani, N.; Younossi, Z.; Lavine, J.E.; et al. (2012). "The diagnosis and management of non-alcoholic fatty liver disease: practice guideline by the American Gastroenterological Association, American Association for the Study of Liver Diseases, and American College of Gastroenterology". Gastroenterology. 142 (7): 1592–1609. {{cite journal}}: Explicit use of et al. in: |last4= (help)
  6. ^ Arab, J.P.; Candia, R.; Zapata, R.; et al. (2014). "Management of nonalcoholic fatty liver disease: an evidence-based clinical practice review". World J Gastroenterol. 20 (34): 12182–12201. {{cite journal}}: Explicit use of et al. in: |last4= (help)
  7. ^ Watanabe, S.; Hashimoto, E.; Ikejima, K.; et al. (2015). "Evidence-based clinical practice guidelines for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis". J Gastroenterol. 50 (4): 364–377. {{cite journal}}: Explicit use of et al. in: |last4= (help)
  8. ^ Bracco, P; Oral, E (2011). "Vitamin E-stabilized UHMWPE for total joint implants: A review". Clinical Orthopaedics and Related Research®. 469 (8): 2286–93. doi:10.1007/s11999-010-1717-6. PMC 3126938. PMID 21132413.
  9. ^ Floridi, A.; Piroddi, M.; Pilolli, F.; Matsumoto, Y.; Aritomi, M.; Galli, F. (2009). "Analysis method and characterization of the antioxidant capacity of vitamin E-interactive polysulfone hemodialyzers". Acta Biomaterialia. 5 (8): 2974–2982. doi:10.1016/j.actbio.2009.04.011.
  10. ^ "Vitamin E as a functional and biocompatibility modifier of synthetic hemodialyzer membranes: an overview of the literature on vitamin E-modified hemodialyzer membranes". Am J Nephrol. 35: 559-72. 2012. doi:10.1159/000338807. {{cite journal}}: Cite uses deprecated parameter |authors= (help)

-- Francesco Galli (talk)

well whatever you did above, has broken the formatting on this page. i spent some time trying to figure it out but i cannot.
and this is kind of the issue. there a bunch of messages above that you haven't read. you haven't tried to learn how things work here, and now you are just leaving angry. that is kind of silly and a waste but so be it. Jytdog (talk) 09:07, 28 August 2017 (UTC)[reply]

plase remove my page and stay out of my businessFrancesco Galli (talk)

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