User talk:Mikael Häggström

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2007, 2008-2013, 2014-2016


Blood Concentration Reference Values[edit]

I am a high school student working on a project regarding compiling reference ranges for blood metabolites. How did you generate the graph seen on that page? (https://en.wikipedia.org/wiki/File:Blood_values_sorted_by_mass_and_molar_concentration.png) Thanks. Dcatanzaro (talk) 17:03, 21 July 2016 (UTC)

Hi, Dcatanzaro! If you're looking for a shortcut, I'm sad to say I don't know any - I created each box, one at a time, in Inkscape. Mikael Häggström (talk) 18:08, 21 July 2016 (UTC)
Oh goodness how long did that take you? Thanks for the quick response! I'll try to find some graphing software and if I have any more questions I'll ask you. Thanks! Dcatanzaro (talk) 19:06, 21 July 2016 (UTC)
I didn't count Face-smile.svg but I think it was worth it since it helped me learn them. Mikael Häggström (talk) 19:32, 21 July 2016 (UTC)

Effects of vaping, compared to tobacco smoking[edit]

  • Switching from tobacco to vaping
-reduced weight gain after smoking cessation[1]
-increased exercise tolerance[1]
-reduced risk of death[2]
  1. ^ a b Sanford Z, Goebel L (2014). "E-cigarettes: an up to date review and discussion of the controversy". W V Med J. 110 (4): 10–5. PMID 25322582. 
  2. ^ Caponnetto, P.; Russo, C.; Bruno, C.M.; Alamo, A.; Amaradio, M.D.; Polosa, R. (2015). "Electronic cigarette: a possible substitute for cigarette dependence". Monaldi Archives for Chest Disease. 79 (1). doi:10.4081/monaldi.2013.104. ISSN 1122-0643. PMID 23741941. 

I found some additional information for the image. QuackGuru (talk) 21:19, 25 July 2016 (UTC)

Thanks! I've added these to the image. Mikael Häggström (talk) 05:10, 26 July 2016 (UTC)
I noticed there is an extra space between -Reduced mortality and Mouth and airways and an extra space between -Reduced cough and Lungs.[1] I do not know if this was intentional to make the image look better. The other image does not have the extra spaces. QuackGuru (talk) 19:04, 7 August 2016 (UTC)
These extra spaces were basically an effect of a lower amount of entries in the image, which even required a considerable increased height for the Adverse effects of vaping image. Mikael Häggström (talk) 19:15, 7 August 2016 (UTC)

Adverse effects of vaping[edit]

  • Eyes:
  • Eye irritation[1] and blurry vision[2]
  • Corneoscleral lacerations or ocular burns after e-cigarette explosion[3]
  • Airways:
  • Irritation and cough[4]
  • Increased airway resistance[5][6]
  • Stomach:
  • Nausea and vomiting[4][6]
  • Abdominal pain[2]
  • Heart and circulation:
  • Chest pain[6]
  • Increased blood pressure[6]
  • Increased heart rate[6]
Mortality:
  • Death after accidental nicotine poisoning[1]
  • Death after intentional ingestion or injection of e-liquid nicotine[7]
  • Death after e-cigarette explosion (small risk)[3]

References

  1. ^ a b Biyani, S; Derkay, CS (28 April 2015). "E-cigarettes: Considerations for the otolaryngologist.". International journal of pediatric otorhinolaryngology. doi:10.1016/j.ijporl.2015.04.032. PMID 25998217. 
  2. ^ a b Breland, Alison B.; Spindle, Tory; Weaver, Michael; Eissenberg, Thomas (2014). "Science and Electronic Cigarettes". Journal of Addiction Medicine. 8 (4): 223–233. doi:10.1097/ADM.0000000000000049. ISSN 1932-0620. PMC 4122311free to read. PMID 25089952. 
  3. ^ a b Paley, Grace L.; Echalier, Elizabeth; Eck, Thomas W.; Hong, Augustine R.; Farooq, Asim V.; Gregory, Darren G.; Lubniewski, Anthony J. (2016). "Corneoscleral Laceration and Ocular Burns Caused by Electronic Cigarette Explosions". Cornea. 35 (7): 1015–1018. doi:10.1097/ICO.0000000000000881. ISSN 0277-3740. PMC 4900417free to read. PMID 27191672. 
  4. ^ a b Grana, R; Benowitz, N; Glantz, SA (13 May 2014). "E-cigarettes: a scientific review.". Circulation. 129 (19): 1972–86. doi:10.1161/circulationaha.114.007667. PMC 4018182free to read. PMID 24821826. 
  5. ^ Ebbert, Jon O.; Agunwamba, Amenah A.; Rutten, Lila J. (2015). "Counseling Patients on the Use of Electronic Cigarettes". Mayo Clinic Proceedings. 90 (1): 128–134. doi:10.1016/j.mayocp.2014.11.004. ISSN 0025-6196. PMID 25572196. 
  6. ^ a b c d e Orellana-Barrios, Menfil A.; Payne, Drew; Mulkey, Zachary; Nugent, Kenneth (2015). "Electronic cigarettes-a narrative review for clinicians". The American Journal of Medicine. doi:10.1016/j.amjmed.2015.01.033. ISSN 0002-9343. PMID 25731134. 
  7. ^ Hua, My; Talbot, Prue (2016). "Potential health effects of electronic cigarettes: A systematic review of case reports". Preventive Medicine Reports. 4: 169–178. doi:10.1016/j.pmedr.2016.06.002. ISSN 2211-3355. PMC 4929082free to read. PMID 27413679. 

The new information is:

  • Eyes:
  • Eye irritation and blurry vision
  • Corneoscleral lacerations or ocular burns after e-cigarette explosion
  • Stomach:
  • Abdominal pain
Mortality:
  • Death after accidental nicotine poisoning
  • Death after intentional ingestion or injection of e-liquid nicotine
  • Death after e-cigarette explosion

I found additional information for the other image. QuackGuru (talk) 18:49, 26 July 2016 (UTC)

I've now added entries to the image. I added effects of possible explosion for the eyes, but I'm not sure the death rate is any notable from e-cigarette explosions. Also, the poisoning part does not only confer mortality but a series of Nicotine poisoning symptoms which may better have a separate image. Mikael Häggström (talk) 16:07, 30 July 2016 (UTC)
  • Death after e-cigarette explosion (small risk)
I think we can still include death after an e-cigarette explosion as long as we state it is a "small risk". QuackGuru (talk) 18:23, 30 July 2016 (UTC)
We can, but I still think it fits better in the article text, since it doesn't fit conveniently into the diagram. Mikael Häggström (talk) 18:03, 7 August 2016 (UTC)
The text will work for the safety of e-cigs article. QuackGuru (talk) 19:04, 7 August 2016 (UTC)

Effects of e-cigarette and e-liquid nicotine poisoning[edit]

Nicotine poisoning:
  • Nicotine poisoning related to e-cigarettes include ingestion, inhalation, or absorption via the skin or eyes.[1]
  • E-cigarette calls to US poison control centers:
  • Minor, moderate, and serious adverse effects involved children and adults.[2] Minor effects correlated with e-cigarette liquid poisoning were tachycardia, tremor, chest pain and hypertension.[3] More serious effects were bradycardia, hypotension, nausea, respiratory paralysis, atrial fibrillation and dyspnea.[3] The exact correlation is not fully known between these effects and e-cigarettes.[3] More than 50% of e-cigarette calls to US poison control centers were related to young children.[2]
  • The most frequent adverse effects to e-cigarettes and e-liquid reported to US poison control centers:
  • Ingestion exposure resulted in vomiting, nausea, drowsy, tachycardia, or agitation.[2]
  • Inhalation/nasal exposure resulted in nausea, vomiting, dizziness, agitation, or headache.[2]
  • Ocular exposure resulted in eye irritation or pain, red eye or conjunctivitis, blurred vision, headache, or corneal abrasion.[2]
  • Multiple routes of exposure resulted in eye irritation or pain, vomiting, red eye or conjunctivitis, nausea, or cough.[2]
  • Dermal exposure resulted in nausea, dizziness, vomiting, headache, or tachycardia.[2]
  • Most e-cigarette calls were a minor effect.[2] Severe outcomes were more than 2.5 times more frequent in children exposed to e-cigarettes and nicotine e-liquid than with traditional cigarettes.[4]
  • Accidental poisoning can result from using undiluted concentrated nicotine when mistakenly used as prepared e-liquids.[5]
  • Death to child after accidental nicotine poisoning[6]
  • Death after intentional ingestion or injection of e-liquid nicotine[7]
  • Between January 1, 2016 and April 30, 2016, the American Association of Poison Control Centers (AAPCC) reported 623 exposures related to e-liquid.[8] The AAPCC recorded 3,783 reported "exposure" incidents relating to liquid nicotine in 2014.[9] The number decreased to 3,067 in 2015.[9]

A separate image for e-cigarette and e-liquid nicotine poisoning is a wonderful idea. QuackGuru (talk) 18:23, 30 July 2016 (UTC)

Agree. It should be ready by the weekend. Mikael Häggström (talk) 05:24, 3 August 2016 (UTC)
Thanks. I added some more information that might be useful. I recommend an image or an outline of a child be used for the new nicotine poisoning image. QuackGuru (talk) 06:20, 3 August 2016 (UTC)
Good! I don't have a fitting child image for these types of diagrams, so it will be using the female template for now. Mikael Häggström (talk) 20:26, 3 August 2016 (UTC)
Symptoms of nicotine poisoning.<ref>References are located at image page in Wikimedia Commons.</ref>
@QuackGuru: Yes check.svg Done. I added it to Nicotine_poisoning#Signs_and_symptoms. In addition, it seems you have gathered lots of additional information which would probably fit into the prose of that section. Mikael Häggström (talk) 18:03, 7 August 2016 (UTC)
I am working on the safety of e-cigs article. I am not sure what is best for the Nicotine poisoning article. QuackGuru (talk) 19:04, 7 August 2016 (UTC)
I added some info to the Nicotine poisoning article. QuackGuru (talk) 22:30, 17 August 2016 (UTC)

────────────────────────────────────────────────────────────────────────────────────────────────────Please see: "Table 4 Most common health effect in e-cigarette calls to U.S. poison centers by exposure route, September 1, 2010–December 31, 2014"[2] "Corneal abrasion 6 (2.0)"[2]

  1. ^ Brandon, T. H.; Goniewicz, M. L.; Hanna, N. H.; Hatsukami, D. K.; Herbst, R. S.; Hobin, J. A.; Ostroff, J. S.; Shields, P. G.; Toll, B. A.; Tyne, C. A.; Viswanath, K.; Warren, G. W. (2015). "Electronic Nicotine Delivery Systems: A Policy Statement from the American Association for Cancer Research and the American Society of Clinical Oncology" (PDF). Clinical Cancer Research. 21: 514–525. doi:10.1158/1078-0432.CCR-14-2544. ISSN 1078-0432. PMID 25573384. 
  2. ^ a b c d e f g h i j Chatham-Stephens, Kevin; Law, Royal; Taylor, Ethel; Kieszak, Stephanie; Melstrom, Paul; Bunnell, Rebecca; Wang, Baoguang; Day, Hannah; Apelberg, Benjamin; Cantrell, Lee; Foster, Howell; Schier, Joshua G. (June 2016). "Exposure Calls to U. S. Poison Centers Involving Electronic Cigarettes and Conventional Cigarettes—September 2010–December 2014". Journal of Medical Toxicology. doi:10.1007/s13181-016-0563-7. ISSN 1556-9039. PMID 27352081. 
  3. ^ a b c Nelluri, Bhargava Krishna; Murphy, Katie; Mookadam, Farouk (2015). "Electronic cigarettes and cardiovascular risk: hype or up in smoke?". Future Cardiology. 11 (3): 271–273. doi:10.2217/fca.15.13. ISSN 1479-6678. PMID 26021631. 
  4. ^ Kamboj, A.; Spiller, H. A.; Casavant, M. J.; Chounthirath, T.; Smith, G. A. (2016). "Pediatric Exposure to E-Cigarettes, Nicotine, and Tobacco Products in the United States". PEDIATRICS. 137 (6): e20160041–e20160041. doi:10.1542/peds.2016-0041. ISSN 0031-4005. PMID 27244861. 
  5. ^ Kaisar, Mohammad Abul; Prasad, Shikha; Liles, Tylor; Cucullo, Luca (2016). "A Decade of e-Cigarettes: Limited Research & Unresolved Safety Concerns". Toxicology. doi:10.1016/j.tox.2016.07.020. ISSN 0300-483X. PMID 27477296. 
  6. ^ Biyani, S; Derkay, CS (28 April 2015). "E-cigarettes: Considerations for the otolaryngologist.". International journal of pediatric otorhinolaryngology. doi:10.1016/j.ijporl.2015.04.032. PMID 25998217. 
  7. ^ Hua, My; Talbot, Prue (2016). "Potential health effects of electronic cigarettes: A systematic review of case reports". Preventive Medicine Reports. 4: 169–178. doi:10.1016/j.pmedr.2016.06.002. ISSN 2211-3355. PMC 4929082free to read. PMID 27413679. 
  8. ^ Smith, L; Brar, K; Srinivasan, K; Enja, M; Lippmann, S (June 2016). "E-cigarettes: How "safe" are they?". The Journal of Family Practice. 65 (6): 380–385. PMID 27474819. 
  9. ^ a b "Electronic Cigarettes and Liquid Nicotine Data" (PDF). American Association of Poison Control Centers. Retrieved 9 January 2016. 

The content is verified. QuackGuru (talk) 19:50, 7 August 2016 (UTC)

Thanks! I reinserted the term. Mikael Häggström (talk) 20:03, 7 August 2016 (UTC)
I hope later on or next year you can update the nicotine poisoning image with an image of a young girl. QuackGuru (talk) 20:55, 7 August 2016 (UTC)

Deaths by age group fixed[edit]

Hi Mikael Häggström,

I've uploaded Commons:File:Deaths by age group fixed.png on Commons, derived from your excel file linked from Commons:File:Deaths by age group.png, because there appeared to be an error in the right-most four cause clusters in the source excel file: the spreadsheet cell formulae were shifted one to the right resulting in an incorrect chart (mainly affecting the causes motor vehicle accidents and firearms). I've also uploaded a few versions of the fixed spreadsheet to my mediafire shared folder in case other charts are needed. Cheers. -84user (talk) 09:43, 26 July 2016 (UTC)

Thanks Face-smile.svg Mikael Häggström (talk) 09:52, 26 July 2016 (UTC)

A cup of coffee for you![edit]

Cup-o-coffee-simple.svg Thank you for your considerable activity on the Wikiversity Journal of Medicine!
Brylie Christopher Oxley (talk) 19:12, 4 August 2016 (UTC)
Thanks Face-smile.svg Mikael Häggström (talk) 19:51, 4 August 2016 (UTC)

Activity related to mapping the human brain?[edit]

Mikael, Are you aware of any efforts or projects related to the human brain? Particularly of interest would be projects attempting to describe brain functional networks.

I am located in Tampere, Finland, so it is nice to connect with people in the Nordic countries.

Brylie Christopher Oxley (talk) 19:17, 4 August 2016 (UTC)

Hello Brylie,
I'm afraid I don't, but you may find such a project at Wikipedia:WikiProject Neuroscience.
Mikael Häggström (talk) 19:55, 4 August 2016 (UTC)

I left a question on your meta talk page[edit]

See: m:User_talk:Mikael_Häggström#How_does_one_get_a_meta-wiki_project_started.3F

I was showing some of my students the effort to create open-source journals, and wondered if it was difficult to establish the project page over at the wiki. We will be watching that page over the next few days.--Guy vandegrift (talk) 17:55, 23 September 2016 (UTC)

I have now replied there. Mikael Häggström (talk) 18:56, 23 September 2016 (UTC)