VARS

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VARS1
Identifiers
Aliases	VARS1, VARS, NDMSCA, valyl-tRNA synthetase 1, G7A, VARS2, valyl-tRNA synthetase
External IDs	OMIM: 192150; MGI: 90675; HomoloGene: 4587; GeneCards: VARS1; OMA:VARS1 - orthologs
Gene location (Human) Chr. Chromosome 6 (human) Band 6p21.33 Start 31,777,518 bp End 31,795,752 bp
Gene location (Mouse) Chr. Chromosome 17 (mouse) Band 17 B1|17 18.54 cM Start 35,219,963 bp End 35,235,298 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right testis left testis islet of Langerhans pituitary gland ganglionic eminence appendix anterior pituitary stromal cell of endometrium gastrocnemius muscle muscle tissue Top expressed in spermatid ventricular zone tail of embryo seminiferous tubule epiblast yolk sac spermatocyte lip tibiofemoral joint otic vesicle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function aminoacyl-tRNA ligase activity nucleotide binding ligase activity protein binding ATP binding aminoacyl-tRNA editing activity valine-tRNA ligase activity Cellular component cytoplasm cytosol Biological process tRNA aminoacylation for protein translation protein biosynthesis valyl-tRNA aminoacylation aminoacyl-tRNA metabolism involved in translational fidelity Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 7407 22321 Ensembl ENSG00000226589 ENSG00000096171 ENSG00000231945 ENSG00000227686 ENSG00000204394 ENSG00000224264 ENSG00000231116 ENSMUSG00000007029 UniProt P26640 Q9Z1Q9 RefSeq (mRNA) NM_006295 NM_011690 RefSeq (protein) NP_006286 NP_006286.1 NP_035820 Location (UCSC) Chr 6: 31.78 – 31.8 Mb Chr 17: 35.22 – 35.24 Mb PubMed search
Wikidata
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Valyl-tRNA synthetase is an enzyme that in humans is encoded by the VARS gene.

See also

• Valine-tRNA ligase