VARS

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Did you search for Value-added reseller ..?
VARS
Identifiers
Aliases VARS, G7A, VARS1, VARS2, valyl-tRNA synthetase
External IDs MGI: 90675 HomoloGene: 4587 GeneCards: VARS
RNA expression pattern
PBB GE VARS 201797 s at fs.png

PBB GE VARS 201796 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006295

NM_011690

RefSeq (protein)

NP_006286
NP_006286.1

NP_035820.3
NP_035820

Location (UCSC) Chr 6: 31.78 – 31.8 Mb Chr 17: 35 – 35.02 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Valyl-tRNA synthetase is an enzyme that in humans is encoded by the VARS gene.[3][4]

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. The protein encoded by this gene belongs to class-I aminoacyl-tRNA synthetase family and is located in the class III region of the major histocompatibility complex.[4]

See also[edit]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Bonnefond L, Fender A, Rudinger-Thirion J, Giege R, Florentz C, Sissler M (Mar 2005). "Toward the full set of human mitochondrial aminoacyl-tRNA synthetases: characterization of AspRS and TyrRS". Biochemistry. 44 (12): 4805–16. doi:10.1021/bi047527z. PMID 15779907. 
  4. ^ a b "Entrez Gene: VARS valyl-tRNA synthetase". 

Further reading[edit]