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WDR3

From Wikipedia, the free encyclopedia
WDR3
Identifiers
AliasesWDR3, DIP2, UTP12, WD repeat domain 3
External IDsOMIM: 604737; MGI: 2443143; HomoloGene: 4937; GeneCards: WDR3; OMA:WDR3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006784

NM_175552
NM_001355657

RefSeq (protein)

NP_006775

NP_780761
NP_001342586

Location (UCSC)Chr 1: 117.93 – 117.97 MbChr 3: 100.05 – 100.07 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

WD repeat-containing protein 3 is a protein that in humans is encoded by the WDR3 gene.[5][6]

This gene encodes a nuclear protein containing 10 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, which usually include a trp-asp at the C-terminal end. Proteins belonging to the WD repeat family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000065183Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000033285Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Claudio JO, Liew CC, Ma J, Heng HH, Stewart AK, Hawley RG (Aug 1999). "Cloning and expression analysis of a novel WD repeat gene, WDR3, mapping to 1p12-p13". Genomics. 59 (1): 85–9. doi:10.1006/geno.1999.5858. PMID 10395803.
  6. ^ a b "Entrez Gene: WDR3 WD repeat domain 3".

Further reading

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