WDR36

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WDR36
Identifiers
Aliases WDR36, GLC1G, TA-WDRP, TAWDRP, UTP21, WD repeat domain 36
External IDs MGI: 1917819 HomoloGene: 6536 GeneCards: WDR36
RNA expression pattern
PBB GE WDR36 gnf1h08540 at fs.png

PBB GE WDR36 gnf1h08539 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_139281

NM_001110015
NM_001110016
NM_144863

RefSeq (protein)

NP_644810

n/a

Location (UCSC) Chr 5: 111.09 – 111.13 Mb Chr 18: 32.84 – 32.87 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

WD repeat-containing protein 36 is a protein that in humans is encoded by the WDR36 gene.[3][4][5]

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Mutations in this gene have been associated with adult-onset primary open-angle glaucoma (POAG).[5]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Bernstein KA, Gallagher JE, Mitchell BM, Granneman S, Baserga SJ (Dec 2004). "The small-subunit processome is a ribosome assembly intermediate". Eukaryot Cell. 3 (6): 1619–26. doi:10.1128/EC.3.6.1619-1626.2004. PMC 539036Freely accessible. PMID 15590835. 
  4. ^ Monemi S, Spaeth G, DaSilva A, Popinchalk S, Ilitchev E, Liebmann J, Ritch R, Heon E, Crick RP, Child A, Sarfarazi M (Mar 2005). "Identification of a novel adult-onset primary open-angle glaucoma (POAG) gene on 5q22.1". Hum Mol Genet. 14 (6): 725–33. doi:10.1093/hmg/ddi068. PMID 15677485. 
  5. ^ a b "Entrez Gene: WDR36 WD repeat domain 36". 

Further reading[edit]