ZFYVE16

ZFYVE16
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3T7L
Identifiers
Aliases	ZFYVE16, PPP1R69, zinc finger FYVE-type containing 16
External IDs	OMIM: 608880; MGI: 2145181; HomoloGene: 8826; GeneCards: ZFYVE16; OMA:ZFYVE16 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	80,483,379 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	92,667,376 bp
RNA expression pattern
	Top expressed in
	corpus callosum; ; endothelial cell; ; inferior ganglion of vagus nerve; ; subthalamic nucleus; ; pars reticulata; ; inferior olivary nucleus; ; superior vestibular nucleus; ; C1 segment; ; tibia; ; external globus pallidus;
	Top expressed in
	spermatocyte; ; genital tubercle; ; tail of embryo; ; spermatid; ; granulocyte; ; choroid plexus of fourth ventricle; ; ventricular zone; ; cumulus cell; ; urethra; ; right kidney;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	1-phosphatidylinositol binding; protein binding; phosphatidylinositol-3,4,5-trisphosphate binding; metal ion binding;
Cellular component	endosome; early endosome; early endosome membrane; intracellular membrane-bounded organelle; membrane; cytoplasm; cytosol;
Biological process	regulation of endocytosis; endosomal transport; protein targeting to lysosome; BMP signaling pathway; signal transduction; vesicle organization;
	Sources:Amigo / QuickGO
Orthologs
	9765
	218441
	ENSG00000039319
	ENSMUSG00000021706
	Q7Z3T8
	Q80U44
	NM_001105251; NM_001284236; NM_001284237; NM_014733; NM_001349434
	NM_173392
	NP_001098721; NP_001271165; NP_001271166; NP_055548; NP_001336363
	NP_775568
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc finger FYVE domain-containing protein 16 is a protein that in humans is encoded by the ZFYVE16 gene.^[5]^[6]

Template:PBB Summary

Interactions

ZFYVE16 has been shown to interact with TOM1.^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000039319 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000021706 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Seet LF, Hong W (Nov 2001). "Endofin, an endosomal FYVE domain protein". J Biol Chem. 276 (45): 42445–54. doi:10.1074/jbc.M105917200. PMID 11546807.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ "Entrez Gene: ZFYVE16 zinc finger, FYVE domain containing 16".
^ Seet, Li-Fong; Liu Ningsheng; Hanson Brendon J; Hong Wanjin (Feb 2004). "Endofin recruits TOM1 to endosomes". J. Biol. Chem. 279 (6). United States: 4670–9. doi:10.1074/jbc.M311228200. ISSN 0021-9258. PMID 14613930. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help)CS1 maint: unflagged free DOI (link)

Interactions

References

Further reading