ZFYVE1

ZFYVE1
Identifiers
Aliases	ZFYVE1, DFCP1, PPP1R172, SR3, TAFF1, ZNFN2A1, zinc finger FYVE-type containing 1
External IDs	OMIM: 605471; MGI: 3026685; HomoloGene: 10945; GeneCards: ZFYVE1; OMA:ZFYVE1 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	73,027,131 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	83,643,996 bp
RNA expression pattern
	Top expressed in
	tibialis anterior muscle; ; middle temporal gyrus; ; amniotic fluid; ; mucosa of ileum; ; pancreatic epithelial cell; ; saphenous vein; ; deltoid muscle; ; endothelial cell; ; Pars compacta; ; lateral nuclear group of thalamus;
	Top expressed in
	spermatid; ; seminiferous tubule; ; granulocyte; ; muscle of thigh; ; neural layer of retina; ; hand; ; ventricular zone; ; left lobe of liver; ; spermatocyte; ; decidua;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	zinc ion binding; 1-phosphatidylinositol binding; protein binding; phosphatidylinositol-3,4,5-trisphosphate binding; metal ion binding; phosphatidylinositol-3,4-bisphosphate binding;
Cellular component	perinuclear region of cytoplasm; autophagosome; mitochondria-associated endoplasmic reticulum membrane; Golgi stack; Golgi apparatus; extrinsic component of omegasome membrane; endoplasmic reticulum; membrane; phagophore assembly site; omegasome;
Biological process	negative regulation of phosphatase activity; cellular response to starvation; macroautophagy;
	Sources:Amigo / QuickGO
Orthologs
	53349
	217695
	ENSG00000165861
	ENSMUSG00000042628
	Q9HBF4
	Q810J8
	NM_001281734; NM_001281735; NM_021260; NM_178441
	NM_183154; NM_001359166; NM_001359167; NM_001359168
	NP_001268663; NP_001268664; NP_067083; NP_848535
	NP_898977; NP_001346095; NP_001346096; NP_001346097
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc finger FYVE domain-containing protein 1 is a protein that in humans is encoded by the ZFYVE1 gene.^[5]^[6]^[7]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000165861 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000042628 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Derubeis AR, Young MF, Jia L, Robey PG, Fisher LW (Nov 2000). "Double FYVE-containing protein 1 (DFCP1): isolation, cloning and characterization of a novel FYVE finger protein from a human bone marrow cDNA library". Gene. 255 (2): 195–203. doi:10.1016/S0378-1119(00)00303-6. PMID 11024279.
^ Cheung PC, Trinkle-Mulcahy L, Cohen P, Lucocq JM (Mar 2001). "Characterization of a novel phosphatidylinositol 3-phosphate-binding protein containing two FYVE fingers in tandem that is targeted to the Golgi". Biochem J. 355 (Pt 1): 113–21. doi:10.1042/0264-6021:3550113. PMC 1221718. PMID 11256955.
^ "Entrez Gene: ZFYVE1 zinc finger, FYVE domain containing 1".

References

Further reading