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Zinc finger, FYVE domain containing 27 is a protein that in humans is encoded by the ZFYVE27 gene.
[5]
Function
This gene encodes a protein with several Transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote Neuriteformation. A mutation in this gene has been reported to be associated with Hereditary spastic paraplegia, however the Pathogenicity of the mutation, which may simply represent a Polymorphism (biology), is unclear. [provided by RefSeq, Mar 2010].
Shirane, M; Nakayama, K. I. (2006). "Protrudin induces neurite formation by directional membrane trafficking". Science. 314 (5800): 818–21. doi:10.1126/science.1134027. PMID17082457.