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zinc finger protein 703
Symbol ZNF703
Entrez 80139
HUGO 25883
RefSeq NM_025069
Other data
Locus Chr. 8 p12

ZNF703[1] is a gene which has been linked with the development of breast cancers.[2][3][4]

Following research by scientists at Cancer Research UK, it was the first oncogene discovery in the past five years.[3]


  1. ^ http://www.ebi.ac.uk/gxa/gene?gid=Q9H7S9
  2. ^ Sircoulomb F, Nicolas N, Ferrari A et al. (February 2011). "ZNF703 gene amplification at 8p12 specifies luminal B breast cancer". EMBO Molecular Medicine 3 (3): 153–166. doi:10.1002/emmm.201100121. PMC 3395112. PMID 21328542. 
  3. ^ a b "BBC News - Key breast cancer 'driver' gene found". 2011-02-18. Retrieved 2011-02-18. 
  4. ^ Kwek SS, Roy R, Zhou H et al. (April 2009). "Co-amplified genes at 8p12 and 11q13 in breast tumors cooperate with two major pathways in oncogenesis". Oncogene 28 (17): 1892–903. doi:10.1038/onc.2009.34. PMC 2722962. PMID 19330026.