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ZNF746

From Wikipedia, the free encyclopedia
ZNF746
Identifiers
AliasesZNF746, P.A.R.I.S, PARIS, zinc finger protein 746
External IDsOMIM: 613914; MGI: 1916478; HomoloGene: 19783; GeneCards: ZNF746; OMA:ZNF746 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001163474
NM_152557
NM_001363517
NM_001394198

NM_001163475
NM_001347142
NM_001362062

RefSeq (protein)

NP_001156946
NP_689770
NP_001350446

NP_001156947
NP_001334071
NP_001348991

Location (UCSC)Chr 7: 149.47 – 149.5 MbChr 6: 48.04 – 48.06 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Zinc finger protein 746 also known as Parkin-interacting substrate (PARIS) is a zinc finger protein that, in humans, is encoded by the ZNF746 gene and is involved in the neurodegeneration of Parkinson's disease.[5][6]


References

[edit]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000181220Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000057691Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Shin JH, Ko HS, Kang H, Lee Y, Lee YI, Pletinkova O, et al. (March 2011). "PARIS (ZNF746) repression of PGC-1α contributes to neurodegeneration in Parkinson's disease". Cell. 144 (5): 689–702. doi:10.1016/j.cell.2011.02.010. PMC 3063894. PMID 21376232.
  6. ^ "Entrez Gene: ZNF746 zinc finger protein 746 [ Homo sapiens (human) ]".