ZNRF1

ZNRF1
Identifiers
Aliases	ZNRF1, NIN283, zinc and ring finger 1, E3 ubiquitin protein ligase, zinc and ring finger 1
External IDs	OMIM: 612060; MGI: 2177308; HomoloGene: 41858; GeneCards: ZNRF1; OMA:ZNRF1 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	75,110,994 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	112,352,662 bp
RNA expression pattern
	Top expressed in
	thymus; ; mucosa of pharynx; ; body of tongue; ; secondary oocyte; ; gingival epithelium; ; pancreatic ductal cell; ; quadriceps femoris muscle; ; vastus lateralis muscle; ; Skeletal muscle tissue of rectus abdominis; ; muscle of thigh;
	Top expressed in
	granulocyte; ; thymus; ; superior surface of tongue; ; gallbladder; ; superior frontal gyrus; ; neural layer of retina; ; primary visual cortex; ; dentate gyrus of hippocampal formation granule cell; ; muscle of thigh; ; lip;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; ubiquitin protein ligase activity; metal ion binding; ubiquitin-protein transferase activity; transferase activity;
Cellular component	endosome; cell junction; lysosome; synapse; synaptic vesicle membrane; membrane; cytoplasmic vesicle; cytosol;
Biological process	protein K48-linked ubiquitination; protein ubiquitination; protein polyubiquitination; proteasome-mediated ubiquitin-dependent protein catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	84937
	170737
	ENSG00000186187
	ENSMUSG00000033545
	Q8ND25
	Q91V17
	NM_032268
NM_001168621; NM_001168622; NM_001168623; NM_133206; NM_001363488;
	NM_001363489
	NP_115644
NP_001162092; NP_001162093; NP_001162094; NP_573469; NP_001350417;
	NP_001350418
	Wikidata
View/Edit Human	View/Edit Mouse

E3 ubiquitin-protein ligase ZNRF1 is an enzyme that in humans is encoded by the ZNRF1 gene.^[5]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000186187 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000033545 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: ZNRF1 zinc and ring finger 1".

References

Further reading