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Zonadhesin

From Wikipedia, the free encyclopedia
ZAN
Identifiers
AliasesZAN, zonadhesin (gene/pseudogene), zonadhesin
External IDsOMIM: 602372; MGI: 106656; HomoloGene: 124417; GeneCards: ZAN; OMA:ZAN - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_011741

RefSeq (protein)

NP_003377
NP_775082

n/a

Location (UCSC)Chr 7: 100.73 – 100.8 MbChr 5: 137.38 – 137.48 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Zonadhesin is a protein that in humans is encoded by the ZAN gene. [5]

Function

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This gene encodes a protein that functions in the species specificity of sperm adhesion to the egg zona pellucida. The encoded protein is located in the acrosome and may be involved in signaling or gamete recognition.

An allelic polymorphism in this gene results in both functional and frameshifted alleles; the reference genome represents the functional allele. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2015].

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000146839Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000079173Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Zonadhesin (gene/pseudogene)". Retrieved 2018-06-28.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.