Suberoyl chloride

Suberoyl chloride

Names
Preferred IUPAC name Octanedioyl dichloride
Other names Suberoyl dichloride; Suberic acid chloride
Identifiers
CAS Number	10027-07-3
3D model (JSmol)	Interactive image
ChemSpider	465767
ECHA InfoCard	100.156.463
PubChem CID	534653
UNII	TG5X3247UL Y
CompTox Dashboard (EPA)	DTXSID10143078
InChI InChI=1S/C8H12Cl2O2/c9-7(11)5-3-1-2-4-6-8(10)12/h1-6H2 Key: PUIBKAHUQOOLSW-UHFFFAOYSA-N
SMILES C(CCCC(=O)Cl)CCC(=O)Cl
Properties
Chemical formula	C8H12Cl2O2
Molar mass	211.08 g·mol−1
Density	1.172 g/cm3
Boiling point	162–163 °C (324–325 °F; 435–436 K)
Solubility in water	Reacts with water
Hazards
GHS labelling:
Pictograms
Signal word	Danger
Hazard statements	H314
Precautionary statements	P260, P264, P280, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P363, P405, P501
Flash point	110 °C (230 °F; 383 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Suberoyl chloride is an organic compound with the formula (CH₂)₆(COCl)₂. It is the diacid chloride derivative of suberic acid. It is a colorless liquid although aged samples appear yellow or even brown.

Uses

Suberoyl chloride is used as a reagent to synthesize hydroxyferrocifen hybrid compounds that have antiproliferative activity against triple negative breast cancer cells. It is also used as a cross-linking agent to cross-link chitosan membranes, and also improves the membrane's integrity.

External links

• MSDS Safety data (PDF)