Putrescine N-methyltransferase: Difference between revisions
Content deleted Content added
m →References: Sort into more specific stub template based on presence in Category:EC 2.1 (Task 25) |
Artoria2e5 (talk | contribs) No edit summary |
||
| Line 15: | Line 15: | ||
Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[S-Adenosyl methionine|S-adenosyl methionine]] and [[putrescine]], whereas its two [[product (chemistry)|products]] are [[S-adenosylhomocysteine]] and [[N-methylputrescine]]. |
Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[S-Adenosyl methionine|S-adenosyl methionine]] and [[putrescine]], whereas its two [[product (chemistry)|products]] are [[S-adenosylhomocysteine]] and [[N-methylputrescine]]. |
||
This enzyme belongs to the family of [[transferase]]s, specifically those transferring one-carbon group methyltransferases. The [[List of enzymes|systematic name]] of this enzyme class is '''S-adenosyl-L-methionine:putrescine N-methyltransferase'''. This enzyme is also called '''putrescine methyltransferase'''. This enzyme participates in [[alkaloid biosynthesis ii]]. |
This enzyme belongs to the family of [[transferase]]s, specifically those transferring one-carbon group methyltransferases. The [[List of enzymes|systematic name]] of this enzyme class is '''S-adenosyl-L-methionine:putrescine N-methyltransferase'''. This enzyme is also called '''putrescine methyltransferase'''. This enzyme participates in [[alkaloid biosynthesis ii]]. |
||
This enzyme is important in the synthesis of many plant [[alkaloid]]s. <ref>{{cite journal | vauthors = Biastoff S, Brandt W, Dräger B | title = Putrescine N-methyltransferase--the start for alkaloids | journal = Phytochemistry | volume = 70 | issue = 15–16 | pages = 1708–18 | date = 2009-10-01 | pmid = 19651420 | doi = 10.1016/j.phytochem.2009.06.012 | series = Evolution of Metabolic Diversity }}</ref> It evolved from [[spermidine synthase]]. <ref>{{cite journal | vauthors = Junker A, Fischer J, Sichhart Y, Brandt W, Dräger B | title = Evolution of the key alkaloid enzyme putrescine N-methyltransferase from spermidine synthase | journal = Frontiers in Plant Science | volume = 4 | pages = 260 | date = 2013-01-01 | pmid = 23908659 | doi = 10.3389/fpls.2013.00260 | pmc=3725402}}</ref> |
|||
==References== |
==References== |
||
Revision as of 21:42, 25 March 2019
| putrescine N-methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.1.1.53 | ||||||||
| CAS no. | 9075-39-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a putrescine N-methyltransferase (EC 2.1.1.53) is an enzyme that catalyzes the chemical reaction
- S-adenosyl-L-methionine + putrescine S-adenosyl-L-homocysteine + N-methylputrescine
Thus, the two substrates of this enzyme are S-adenosyl methionine and putrescine, whereas its two products are S-adenosylhomocysteine and N-methylputrescine.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:putrescine N-methyltransferase. This enzyme is also called putrescine methyltransferase. This enzyme participates in alkaloid biosynthesis ii.
This enzyme is important in the synthesis of many plant alkaloids. [1] It evolved from spermidine synthase. [2]
References
- ^ Biastoff S, Brandt W, Dräger B (2009-10-01). "Putrescine N-methyltransferase--the start for alkaloids". Phytochemistry. Evolution of Metabolic Diversity. 70 (15–16): 1708–18. doi:10.1016/j.phytochem.2009.06.012. PMID 19651420.
- ^ Junker A, Fischer J, Sichhart Y, Brandt W, Dräger B (2013-01-01). "Evolution of the key alkaloid enzyme putrescine N-methyltransferase from spermidine synthase". Frontiers in Plant Science. 4: 260. doi:10.3389/fpls.2013.00260. PMC 3725402. PMID 23908659.
{{cite journal}}: CS1 maint: unflagged free DOI (link)
- Mizusaki S, Tanabe Y, Noguchi M, Tamaki E (1971). "Phytochemical studies on tobacco alkaloids. XIV. The occurrence and properties of putrescine N-methyltransferase in tobacco roots". Plant Cell Physiol. 12: 633–640.