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(+)-Caryolan-1-ol synthase

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(+)-Caryolan-1-ol synthase
Identifiers
EC no.4.2.1.138
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
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NCBIproteins

(+)-Caryolan-1-ol synthase (EC 4.2.1.138, GcoA) is an enzyme with systematic name (+)-beta-caryophyllene hydrolase (cyclizing, (+)-caryolan-1-ol-forming).[1] This enzyme catalyses the following chemical reaction

(+)-beta-caryophyllene + H2O (+)-caryolan-1-ol

This enzyme also forms (+)-beta-caryophyllene from farnesyl diphosphate (EC 4.2.3.89).

References

  1. ^ Nakano, C.; Horinouchi, S.; Ohnishi, Y. (2011). "Characterization of a novel sesquiterpene cyclase involved in (+)-caryolan-1-ol biosynthesis in Streptomyces griseus". J. Biol. Chem. 286: 27980–27987. doi:10.1074/jbc.m111.265652. PMID 21693706.{{cite journal}}: CS1 maint: unflagged free DOI (link)