Jodorowsky started playing piano at the age of six. At the age of seven, he met James Brown at the backstage of a concert. Brown taught Adan how to dance like him.
Jodorowsky's first guitar lessons were given by The Beatles guitarist George Harrison. In this occasion, Harrison told him that "he was far". Adan did not know if "he was far" in an enlightened way or "far" from being a good guitarist. When he was sixteen he joined the punk band The Hellboys. Then he wanted to try another music genre and meet Yarol Poupaud and Adrienne Pauly, Following these encounters he started playing bass.
On October 30, 2006, he released his first solo album, Étoile Éternelle, as "Adanowsky", and his first single, L'idole (meaning "the idol") which was also released in Spanish as El Ídolo; the song is about a waiter who wants all the attention and dreams of becoming famous and an idol.
In 2007, he featured as an actor in the Julie Delpy's movie "2 Days In Paris".
In 2008, he released his second album, El Ídolo and had a big succes in South America, specially in Argentina and Chile.
In 2011 he released his third solo album "Amador" and won the UFI award for "Best International Artist Of The Year" and "Best Live Show". Then he met Devendra Banhart, and together, they recorded the song You are the one and "Dime Cuando" .
He also helped on Alizée's new album, writing a song for her called La Candida.