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Arctostaphylos alpina - Alpine Bearberry
Bearberries are three species of dwarf shrubs in the genus Arctostaphylos. Unlike the other species of Arctostaphylos (see manzanita), they are adapted to Arctic and Subarctic climates, and have a circumpolar distribution in northern North America, Asia and Europe, one with a small highly disjunctive population in Central America.
The name "bearberry" for the plant derives from the edible fruit which is a favorite food of bears. The fruit, also called bearberries, are edible and are sometimes gathered for food. The leaves of the plant are used in herbal medicine.
- Alpine bearberry - A. alpina (L.) Spreng (syn. Arctous alpinus (L.) Niedenzu). A procumbent shrub 10–30 centimetres (3.9–12 in) high. Leaves not winter green, but dead leaves persist on stems for several years. Berries dark purple to black. Distribution: circumpolar, at high latitudes, from Scotland east across Scandinavia, Russia, Alaska, Canada and Greenland; southern limits in Europe in the Pyrenees and the Alps, in Asia to the Altay Mountains, and in North America to British Columbia in the west, and Maine and New Hampshire in the United States in the east.
- Red bearberry - A. rubra (Rehd. & Wilson) Fernald (syn. Arctous rubra (Rehder and E.H. Wilson) Nakai; Arctous alpinus var. ruber Rehd. and Wilson). A procumbent shrub 10–30 centimetres (3.9–12 in) high. Leaves deciduous, falling in autumn to leave bare stems. Berries red. Distribution: in the mountains of Sichuan, southwestern China north and east to eastern Siberia, Alaska and northern Canada east to northern Quebec.
- Common bearberry - A. uva-ursi (L.) Spreng.
Other recorded old English common names include arberry, bear's grape, crowberry, foxberry, hog cranberry, kinnikinnick, mealberry, mountain box, mountain cranberry, mountain tobacco, sandberry, upland cranberry, and uva-ursi.
Uses in folk medicine 
The plant contains arbutin, ursolic acid, tannic acid, gallic acid, some essential oil and resin, hydroquinones (mainly arbutin, up to 17%), tannins (up to 15%), phenolic glycosides and flavonoids.
Bearberry appears to be relatively safe, although large doses may cause nausea, vomiting, fever, chills, severe back pain and tinnitus. It should not be used during pregnancy, breast feeding, or in children or patients with kidney disease.
The efficacy and safety of bearberry treatment in humans remains unproven, despite long-term use in folk medicine. Although human pilot studies exist, there has been no substantual human research conducted.
History and folklore 
Bearberry was first documented in The Physicians of Myddfai, a 13th century Welsh herbal. It was also described by Clusius in 1601, and recommended for medicinal use in 1763 by Gerhard and others. Often called uva-ursi, from the Latin uva, "grape, berry of the vine", ursi, "bear", i.e. "bear's grape". It first appeared in the London Pharmacopoeia in 1788.
In Strathnairn, Scotland there is a hill, known as Brin Mains, but which is known in Scottish Gaelic as "Cnoc nan Cnàimhseag" which means "The hill of the bearberries".
Folk tales suggest Marco Polo thought the Chinese were using it as a diuretic. Bearberry leaves are used medicinally in parts of Europe, and are officially classified as a phytomedicine. Native Americans use bearberry leaves with tobacco and other herbs in religious ceremonies, both as a smudge (type of incense) or smoked in a sacred pipe carrying the smoker's prayers to the Great Spirit. When mixed with tobacco or other herbs, it is referred to as kinnikinnick, from an Algonquian (probably Delaware) word for "mixture". Among the ingredients in kinnikinnick were non-poisonous sumac leaves, and the inner bark of certain bushes such as red osier dogwood (silky cornell), chokecherry, and alder, to improve the taste of the bearberry leaf.
- Schofield, Janice J. (1989) Discovering wild plants: Alaska, western Canada, the Northwest Alaska Northwest Books, page 217, ISBN 978-0-88240-355-7
- Pegg, Ronald B.; Rybarczyk, Anna and Amarowicz, Ryszard (2008) "Chromatographic Separation of Tannin Fractions from a Bearberry-leaf (Arctostaphylos Uva-ursi L. Sprengel) Extract by Se-hplc – a Short Report" Polish Journal of Food and Nutrition Sciences 58(4): pp. 485–490
- Hänsel, Rudolf; Keller, K.; Rimpler, H.; and Schneider, G. (1992) "Uvae ursi folium (Bärentraubenblätter)" In: Hagers Handbuch der pharmazeutischen Praxis: 4, Drogen A - D (5th Edition) Springer-Verlag, Berlin, pp. 330–336, ISBN 3-540-52631-5
- See Bearberry in Blumenthal M, Busse W, Goldberg A, et al. (editors) (1998) The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines American Botanical Council, Austin, Texas, ISBN 978-0-9655555-0-0
- Another herb sometimes recommended for UTI is bearberry, also known as uva ursi. Some concerns about this herb exist. Specifically, it is not clearly effective for UTI prevention, it appears to be less effective with acidic urine, it may cause nausea and vomiting, and it contains chemicals that may have cancer-causing properties. Bowling, Allen C. (2007) Complementary and Alternative Medicine and Multiple Sclerosis (2nd edition) Demos Medical Publishing, New York, page 127, ISBN 978-1-932603-54-5
- Nordeng H. and Havnen, G.C. (2005) "Impact of socio-demographic factors, knowledge and attitude on the use of herbal drugs in pregnancy" Acta Obstetricia et Gynecologica Scandinavica 84(1): pp. 26–33, note 16, doi:10.1111/j.0001-6349.2005.00648.x.
- Borins, M. (1998) "The dangers of using herbs: What your patients need to know" Postgraduate medicine 104(1): pp. 91–95, 99–100.
- Jahodar L., Jilek P., Paktova M., and Dvorakova V. (1985) "Antimicrobial effect of arbutin and an extract of the leaves of Arctostaphylos uva-ursi in vitro" Ceskoslovenska Farmacie 34: pp. 174–178
- Moskalenko S. (1986) "Preliminary screening of far-Eastern ethnomedical plants for antibacterial activity" Journal of Ethnopharmacology 15: pp. 231–259
- Annuk H., Hirmo S., Turi E., Mikelsaar M., Arak E., and Wadstrom T. (1999) "Effect on cell surface hydrophobicity and susceptibility of Helicobacter pylori to medicinal plant extracts" FEMS Microbiology Letters 172: pp. 41–45
- Park S. (1994) "The repression of listeriolysin O expression in Listeria monocytogenes by the phenolic beta-D-glucoside, arbutin" Letters in Applied Microbiology 19: pp. 258–260
- Robertson J. and Howard L. (1987) "Effect of carbohydrates on growth of Ureaplasma urealyticum and Mycoplasma hominis" Journal of Clinical Microbiology 25: pp. 160–161
- Ng T.B., Ling J.M., Wang Z.T., Cai J.N., and Xu G.J. (1996) "Examination of coumarins, flavonoids and polysaccharopeptide for antibacterial activity" General Pharmacology: The Vascular System 27: pp. 1237–1240
- Nikolaev S., SHantanova L., Mondodoev A., Rakshaina M., Lonshakova K., and Glyzin V. (1996) "Pharmacological activity of the dry extract from the leaves for Arctostaphylos uva-ursi L in experimental nephropyelitis" Rastitelnye Resursy (Plant Research) 32: pp. 118–123
- Larsson B., Jonasson A., and Fianu S. (1993) "Prophylactic effect of UVA-E in women with recurrent cystitis: A preliminary report" Current Therap Res Clin Exper 53: pp. 441–443
- Parvez, Shoukat et al. (2006) "Survey and mechanism of skin depigmenting and lightening agents" Phytotherapy Res 20(1): pp.921 –934, doi:10.1002/ptr.1954
- Upham, Warren (2001) Minnesota place names: a geographical encyclopedia (3rd edition) Minnesota Historical Society Press, St. Paul, Minnesota, page 481, ISBN 0-87351-396-7
- Staff (2009) "Bearberry" Discovering Lewis and Clark The Lewis and Clark Fort Mandan Foundation
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